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1.
China Journal of Chinese Materia Medica ; (24): 4011-4018, 2018.
Artigo em Chinês | WPRIM | ID: wpr-775385

RESUMO

Hypolipidemic polysaccharides have notable activity and safety with a range of diverse sources. In this paper, the classification of hypolipidemic polysaccharides was carried out into polysaccharide sulfate, glycosaminoglycan, homopolysaccharide and heteropolysaccharide. The hypolipidemic activity mechanism and structure-activity relationship hypothesis of those polysaccharides in recent years were briefly reviewed therefore to provide references for the study and product development of polysaccharides.


Assuntos
Hipolipemiantes , Química , Farmacologia , Polissacarídeos , Química , Farmacologia , Relação Estrutura-Atividade
2.
China Journal of Chinese Materia Medica ; (24): 1032-1037, 2015.
Artigo em Chinês | WPRIM | ID: wpr-246156

RESUMO

Affinity chromatography is a chromatographic method for separating molecules using the binding characteristics of the stationary phase with potential drug molecules. This method can be performed as a high throughput screening method and a chromatographic separation method to screen a variety of active drugs. This paper summarizes the history of affinity chromatography, screening technology of affinity chromatography, and application of affinity chromatography in screening bio-active compounds in herbal medicines, and then discusses its application prospects, in order to broaden applications of the affinity chromatography in drug screening.


Assuntos
Animais , Humanos , Cromatografia de Afinidade , Métodos , Avaliação Pré-Clínica de Medicamentos , Métodos , Medicamentos de Ervas Chinesas , Química , Farmacologia , Plantas Medicinais , Química
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