RESUMO
OBJECTIVE: To study the diagnostic efficiency of the fine needle aspiration biopsy(FNA) and contrastenhanced ultrasound(CEUS) in differentiation of solid thyroid nodules coexisting Hashimoto's thyroiditis, and to determine whether combined use of both methods is helpful. METHODS: A total of 68 thyroid nodules in 62 patients were observed with CEUS and FNA before surgical excision. The diagnostic performances of FNA, CEUS and CEUS combined with FNA were compared. RESULTS: There was no significant difference in sensitivity, accuracy, positive predictive value and negative predictive value among the three methods(P>0.05). The specificity was significant high in FNA group(P<0.05). CONCLUSION: FNA has high specificity in the diagnosis of Hashimoto's thyroiditis with nodule.FNA combined with CEUS could not improve the diagnostic accuracy for thyroid nodules coexisting Hashimoto's thyroiditis.