RESUMO
OBJECTIVE: To observe the effects of ethanol extracts of Panax notoginseng on the tumor and the liver metastasis in experimental mice grafted with B16 melanoma. METHODS: B16 melanoma was transplanted in the spleen of C57BL/6 mice. The effects of different doses of ethanol extracts of Panax notoginseng on the inhibition rate of spleen tumors and the liver metastasis were observed respectively. RESULTS: The high-, medium-, and low-doses of the extracts and the interferon-alpha (IFN-alpha) can improve the quality of life of the experimental mice. The weights of spleen tumor were lower in the low- and medium-dose extracts-treated groups and the IFN-alpha-treated group than that in the normal saline (NS)-treated group (P<0.05 or P<0.01). The liver metastasis was less in the low- and medium-dose extracts-treated groups and the IFN-alpha-treated group than that in the NS-treated group (P<0.01). CONCLUSION: The ethanol extracts of Panax notoginseng can improve the quality of life of the experimental mice and inhibit the growth of tumor and the liver metastasis.
RESUMO
[Objective]To observe the effect of Decoction for Clearing Away Gallbladder Heat on treating digestive tract reaction,such as nausea and vomiting induced by chemical therapy.[Method] The patients were randomly divided into two groups, and the treatment group(n=40) were treated with Decoction for Clearing Away Gallbladder Heat combined with chemotherapy; while the control group(n=40) with Ondansetron hydrochloric acid combined with chemotherapy.[Result] The treatment group had much less reactions of nausea and vomiting than control one(P