Experience on the research-aimed experiment of undergraduate students / 中华医学教育探索杂志

It is meaningful to prompt the research-aimed experiments in the laboratory edu-cation of undergraduate students majoring in pharmacy,which means under the guidance of tutors, students collect information,design the experiment procedure and conduct the whole experiment independently. Under this novel mode of laboratory education, students’ abilities of indepen-dent-thinking and comprehensive-experimental conduction are largely improved. Meanwhile,the sense of team-work is enhanced. To sum up,the research-aimed experiments is significantly ben-eficial to training undergraduate students for future scientific researches.

The relationship between enhancement degree on spiral computed tomography and the vascular endothelial growth factor and microvessel density expression in colorectal carcinoma / 中华放射学杂志

Objective To investigate the expression of vascular endothelial growth factor (VEGF) and microvessel density (MVD) in colorectal carcinoma, and to study its relationship with the enhancement degree of the lesion on SCT scan. Methods Thirty patients with colorectal carcinoma confirmed by colonofiberscope or operation were examined by SCT, and the CT attenuations were measured. The resected tumor specimens were immunohistochemically stained with CD34 for measuring MVD and stained with VEGF. The results were compared with the enhancement degree of the lesions observed on SCT scan. Results The enhancement correlated well positively with MVD and VEGF of the colorectal carcinoma. The degree of enhancement correlated closely with the blood supply and MVD and VEGF of colorectal carcinoma (r_1=0.5905, P_1=0.0015; r_2=0.4574, P_2=0.0126). Conclusion High expression of VEGF and MVD is a biological label of malignancy(P