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Chinese Journal of Biotechnology ; (12): 1206-1213, 2019.
Artigo em Chinês | WPRIM | ID: wpr-771808

RESUMO

Rolling circle amplification is a rapid, sensitive and isothermal single-stranded DNA amplification technique that can be used with staining or probes to amplify the detection signal. This technology has been widely used in biological detection and other aspects. The present paper introduces how to design rolling circle amplification, summarize its application in the detection of pathogens, nucleic acid tumor markers, proteins, biological small biomolecules, and viruses in recent years and prospects for future development.


Assuntos
DNA de Cadeia Simples , Técnicas de Amplificação de Ácido Nucleico
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