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@#Airway management is important for critically ill patients. Improper airway management can directly threaten the life of patients.[1] Early correct airway assessment and effective airway management can improve patient prognosis.[2] Coughing ability plays an important role in the decision-making process of airway management. Patients with impaired coughing ability have a higher risk of tracheal intubation during treatment. The concept of cough strength was first proposed by Khamiees in 2001,[3] but the evaluation criteria did not include coughing ability. The purpose of this study was to assess patients’ coughing ability through the Delphi method and expert consultation, to provide data support for establishing a cough reflex intensity score and to construct an advanced airway management model for quick and effective evaluation.[4,5]
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OBJECTIVE@#To evaluate the clinical curative effect of acupuncture on unilateral spatial neglect (USN) after stroke.@*METHODS@#Sixty-four patients with left hemiplegia after the first stroke and diagnosed with unilateral spatial neglect after stroke in the right hemisphere were randomly divided into an observation group and a control group, 32 cases in each group. In the control group, conventional acupuncture was used at Jianyu (LI 15), Quchi (LI 11), Shousanli (LI 10), Waiguan (TE 5), Hegu (LI 4), Huantiao (GB 30), Yanglingquan (GB 34), Zusanli (ST 36) and Sanyinjiao (SP 6) on the affected side. In the observation group, acupuncture was applied at Baihui (GV 20), Fengfu (GV 16), Fengchi (GB 20), Xuanzhong (GB 39) and . The treatment was given once a day, 5 times as one course for 4 courses in both groups. The cancellation test, digit cancellation test, bisection line test, clock drawing test, and copying drawing test were used to assess the degree of unilateral spatial neglect, and the Fugl-Meyer motor function scores and the modified Barthel index (MBI) scores were compared before and after treatment in the two groups.@*RESULTS@#After treatment, the scores of cancellation test, digit cancellation test, bisection line test, clock drawing test and copying drawing test were significantly lower than those before treatment in the two groups (all <0.05), and the scores of the above unilateral spatial neglect after treatment in the observation group were lower than those in the control group (all <0.01). After treatment, the scores of Fugl-Meyer motor function and MBI in the two groups were significantly higher than before treatment (all <0.05), and the difference of MBI scores before and after treatment in the observation group was higher than that in the control group (<0.01).@*CONCLUSION@# acupuncture can improve the cognition of unilateral spatial neglect in stroke patients with unilateral spatial neglect, improve the degree of bilateral spatial neglect and the motor function of hemiplegic limbs, and positively promote the improvement of cognitive impairment and self-care ability in daily life.
Assuntos
Humanos , Pontos de Acupuntura , Terapia por Acupuntura , Hemiplegia , Terapêutica , Acidente Vascular Cerebral , Resultado do TratamentoRESUMO
BACKGROUND: Paeonol is an active ingredient of traditional orthopedic drugs, exhibiting pain easing, detumescence and promotion of bone healing. The brushite calcium phosphate cement possesses good biocompatibility, which can be completely degraded in the body. A large number of studies have addressed the modification of brushite calcium phosphate cement to make it more suitable for clinical applications. OBJECTIVE: To study the setting time, syringeability, compressive strength, drug delivery ability, antibacterial property and cell affinity of brushite calcium phosphate cement with the addition of paeonol. METHODS: The tricalcium phosphate was synthesized by calcium nitrate and diammonium hydrogen phosphate, followed by being calcined into β-tricalcium phosphate at 1 000 ℃. Chitosan was dissolved in citric acid solution to prepare the liquid phase. The composite bone cement was prepared by mixing paeonol, β-tricalcium phosphate and monocalcium phosphate with the liquid phase. The setting time, syringeability, phase composition, anti-collapsibility, compressive strength, degradation property, drug delivery ability, antibacterial property and cell affinity of the composite bone cement in vitro were evaluated. RESULTS AND CONCLUSION: The setting time of bone cement was 12-17 minutes, which was prolonged with the increase of paeonol release. Moreover, the loaded paeonol showed no significant effect on the phase composition, syringeability, anti-collapsibility, and compressive strength of the compound. However, the degradation rate and drug release content were significantly enhanced with the increase of paeonol release.The inhibition zone experiments showed that the paeonol loaded cement inhibited the growth of Escherichia coli, but was not sensitive to Staphylococcus aureus.HepG2 cells could adhere and proliferate on the material surface after 3 days co-culture,with clear cell pseudopodia arising from the cell surface under the scanning electron microscope.
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<p><b>OBJECTIVE</b>To compare the difference in effectiveness between the catgut implantation and Fenofibrate for obesity hypertriglyceridemia.</p><p><b>METHODS</b>Seventy-four patients were randomized divided into a catgut implantation group (36 cases) and a medicine group (38 cases). The catgut implantation treatment was applied at the acupoint of Zusanli (ST 36), Fenglong (ST 40), Zhongwan (CV 12), Liangmen (ST 21), Tianshu (ST 25), Quchi (LI 11), Fujie (SP 14), Shangjuxu (ST 37) in catgut implantation group. The treatment of Fenofibrate was used in medicine group. Both treatments last for eight weeks. The level of triglyceride (TG) and the weight were examined in both groups before and after receiving the treatments.</p><p><b>RESULTS</b>The change value of TG was(1.12 +/- 0.65) mmol/L in catgut implantation group, (1.18 +/- 0.62) mmol/L in medicine group,there was no significant difference between two groups. The weight was (73.1 +/- 6.6) kg in catgut implantation group which was significantly lower than (76.2 +/- 8.6) kg in medicine group (P < 0.01) after treatment.</p><p><b>CONCLUSION</b>The effectiveness is comparable in improving the level of hypertriglyceridemia between two groups. The catgut implantation treatment has apparent effect in weight loss; and it is a sound treatment for obesity hypertriglyceridemia.</p>