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Objective To investigate the effect of salmeterol/fluticasone (SM/FP) on serum inflammatory factors in the treatment of bronchial asthma in children.Methods 80 children with bronchial asthma from January 2015 to October 2015 in department of pediatrics of first affiliated hospital of Zhejiang Chinese medicine university were selected and randomly divided into two groups.The control group were given routine clinical treatment, the experimental group were treated on the basis of the control group with salmeterol/fluticasone (SM/FP), for 4 weeks.The serum IL-2, IL-4, IFN-α, T-lymphocyte subsets and clinical efficacy between the two groups were compared.Results Compared with control group, the serum levels of IL-2 and IFN-γin experimental group were higher, IL-4 in experimental group was lower ( P <0.05 ); the serum CD3 +T, CD4 +T and CD4 +T /CD8 +T levels in experimental group were higher, the serum CD8 +T was lower than those in control group (P<0.05); the total efficiency of the experimental group (92.5%) was significantly higher than that of control group (75.0%) (P<0.05).Conclusion The salmeterol/fluticasone (SM/FP) has the good efficacy in the treatment of bronchial asthma in children, which could effectively regulate T lymphocyte subsets proportion and the level of cytokines.
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Objective To explore the effect of colposcopy and LEEP in the treatment of cervical precancerous lesions. Methods A total of 96 patients with cervical precancerous lesions by biopsy directed under colposcopy were operated on by LEEP directed under colposcopy,the average operation time and the average blood loss,the diagnostic accuracy between biopsy directed under colposcopy and LEEP directed under colposcopy were compared. Results The average operation time was (6±0.9)min and the average blood loss was (11.3±2.6)mL.Among 96 cases,88 colposcopic biopsy cases had the same histopathology with LEEP biopsies. Among 96 cases who were followed up by TCT three months later,97.9% of the patients showed normal appearance,and it was up to 100% six months after operation. Conclusion Colposcopy combined LEEP has a high clinical value which has small trauma,less bleeding, short time and remove completely,and it is effectively avoided the excessive medical treatment and lack of treatment,so it is worth to popularize.