Treatment of IntractabIe Cancer Pain with Alcohol Celiac Plexus Block / 대한마취과학회지

Intractable pain from nonresectable or recurrent cancer of upper abdominal organs has been treated in many ways. We chose the method of 50% alcohol celiac plexus block for the pain relief. The results were as follows: 1) It is relatively simple, highly effective, and a less hazardous means of palliative therapy. 2) Satisfactory pain relief was seen in 11 cases (91.7%), excluding 1 case (8.3%) with no improvement in hospitalization state. We concluded this block is remarkably safe as well as effective and should be employed more frequently.

Changes in Serum Potassium after Induction with Propanidid-Succinylcholine / 대한마취과학회지

Three groups of healthy adults were premedicated with diaxepam or secobarbital and anesthetized with propanidid or thiopental. The concentration of serum potassium wes measured before induction and after succinylchaline iodide administration. The increases of potassium in diazepam-thiopental, diaxepam-propanidid and secobarbital propanidid groups were 0. 14, 0. 06, and 0. llmEq/L (3. 29, l. 38 and 2. 58%) respectively. Serum potassium changes were least in diazepam-propanidid group, but there were no significant differences among the 3 groups. The choice of induction agent is of importance for the changes in serum potassium which follow the subsequent injection of succinylcholine iodide. For instance, intravenous induction by barbiturate is followed by a lesser increase in serum potassium after succinylcholine injection than induction by halothane. As barbiturates are so commonly used as intravenous induction agents, we chose thiopental and succinylcholine iodide as standard with which to compare the other induction agents, propanidid and succinylcholine iodode. And also, we wanted compare two premedicants, secobarbital and diaepam. The results were as follows: (1) The thiopental-succinylcholine iodide group and the propaaidid-succinylcholine iodide group revealed no significant differences in serum potassium level. (2) There was a lesser increase in serum potoassium level after premedication with diazepam than premedicstion with secobarbital in the propanidid-succinylcholine iodide group. (3) Induction by propanidid succinylcholine iodide and premedication by diazepam are recommendable for least increasing the serum potassium level.