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Journal of the Korean Society of Biological Psychiatry ; : 46-53, 2008.
Artigo em Coreano | WPRIM | ID: wpr-725077

RESUMO

Posterior cortical atrophy(PCA) is a presenile dementia that presents primarily with signs and symptoms of cortical visual dysfunction, while memory is relatively preserved until the late stage of the disease. We report a patient with PCA, confirmed by brain magnetic resonance imaging (MRI) and F18-fluorodeoxyglucose positron emission tomography(FDG PET). A 58-year-old right-handed woman presented initially with visual dimness and difficulty finding things around her. She had partial Balint's syndrome, partial Gerstmann syndrome, and idiomotor apraxia. She also had a mild memory disturbance, but preserved insight of her disease. Neuropsychological evaluation showed decreased parietal and left temporal functions bilaterally. Brain MRI and F18-FDG PET revealed typical bilateral occipitoparietal atrophy and hypometabolism, which were slightly worse on the right side. Cholinesterase inhibitor administration for 6 months improved the memory impairment slightly, but not the cortical visual dysfunction. This is a typical case of PCA, confirmed by neurologic signs and imaging findings.


Assuntos
Feminino , Humanos , Pessoa de Meia-Idade , Doença de Alzheimer , Apraxias , Atrofia , Encéfalo , Colinesterases , Demência , Elétrons , Síndrome de Gerstmann , Doença de Depósito de Glicogênio Tipo VI , Imageamento por Ressonância Magnética , Memória , Manifestações Neurológicas , Anafilaxia Cutânea Passiva
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