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1.
Endocrinology and Metabolism ; : 70-75, 2013.
Artigo em Inglês | WPRIM | ID: wpr-146598

RESUMO

Atypical antipsychotics have replaced conventional antipsychotics in the treatment of schizophrenia because they have less of a propensity to cause undesirable neurologic adverse events including extrapyramidal symptoms, tardive dyskinesia, and neuroleptic malignant syndrome (NMS). However, atypical antipsychotics have been known to result in various metabolic complications such as impaired glucose tolerance, diabetes and even diabetic ketoacidosis (DKA). In addition, a number of NMS cases have been reported in patients treated with atypical antipsychotics, although the absolute incidence of neurologic side effects is currently significantly low. Here, we report a patient who simultaneously developed DKA, acute renal failure and NMS with rhabdomyolysis after olanzapine treatment. Olanzapine-induced metabolic complications and NMS were dramatically improved with cessation of the olanzapine treatment and initiation of supportive management including fluid therapy, hemodialysis, and intensive glycemic control using insulin. At short-term follow-up, insulin secretion was markedly recovered as evidenced by a restoration of serum C-peptide level, and the patient no longer required any hypoglycemic medications. Despite the dramatic increase in the use of atypical antipsychotics treatment, individualized treatments along with careful monitoring may be prudent for high risk or vulnerable patients in order to avoid the development of metabolic side effects.


Assuntos
Humanos , Injúria Renal Aguda , Antipsicóticos , Benzodiazepinas , Peptídeo C , Cetoacidose Diabética , Hidratação , Seguimentos , Glucose , Incidência , Insulina , Transtornos dos Movimentos , Síndrome Maligna Neuroléptica , Diálise Renal , Rabdomiólise , Esquizofrenia
2.
Journal of Cardiovascular Ultrasound ; : 150-153, 2012.
Artigo em Inglês | WPRIM | ID: wpr-207509

RESUMO

A 41-year-old woman who was diagnosed with myocarditis presented eosinophilia. Since the antibody against Toxocara canis (T. canis) was positive, we diagnosed that she had visceral larva migrans due to T. canis associated with myocarditis. She was treated with oral albendazole and prednisolone for two weeks, eosinophil count and hepatic enzymes were normalized after completion of treatment. This is the first report of myocarditis caused by T. canis infection in Korea.


Assuntos
Adulto , Feminino , Humanos , Albendazol , Eosinofilia , Eosinófilos , Coreia (Geográfico) , Larva Migrans Visceral , Miocardite , Prednisolona , Toxocara , Toxocara canis
3.
The Korean Journal of Helicobacter and Upper Gastrointestinal Research ; : 116-119, 2012.
Artigo em Inglês | WPRIM | ID: wpr-221401

RESUMO

Recent research reveal that the diagnosis of gastric extraluminal compressions mimicking subepithelial tumor is increasing in numbers as esophagogastroduodenoscopy becomes widespread. Endoscopic ultrasonography is a very useful tool for differentiating extraluminal compressions from subepithelial tumors. Gastric extraluminal compressions are due to compression by either normal adjacent organs or pathologic conditions. Pathologic conditions are mainly benign, but some requires operation according to its size. We report a case of a 24-year-old female, who underwent esophagogastroduodenoscopy and was misdiagnosed with gastric subepithelial tumor. Endoscopic ultrasonographic findings showed anechoic cyst outside the gastric wall, which revealed to be a splenic cyst.


Assuntos
Feminino , Humanos , Adulto Jovem , Endoscopia do Sistema Digestório , Endossonografia
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