A randomized controlled study of hypofractionated radiotherapy and conventional fractionated radiotherapy combined with chemotherapy in the treatment of postoperative tracheoesophageal groove lymph node metastasis / 中华放射医学与防护杂志

Objective@#To investigate the efficiency and safety of hypofractionated radiotherapy (HFR) combined with chemotherapy using paclitaxel for the treatment of esophageal cancer (EC) patients with post-operative tracheoesophageal groove lymph node (TGLN) metastasis.@*Methods@#A total of fifty-three post-operative EC patients with TGLN metastasis were randomly divided into HFR group (n=25), receiving a radiation of 60 Gy/20 fractions, and conventional fractionated radiotherapy (CFR) group (n=28), receiving a radiation of 60 Gy/30 fractions combined with chemotherapy using paclitaxel with a dosage of 50 mg once per week through tossing a coin. the adverse events and the prognosis between two groups were compared.@*Results@#The incidence of radiation esophagitis and pneumonitis (grade 3-4) between the HFR group and CFR group showed no statistically significant difference (44.0%, 25.0%, P>0.05; 16.0%, 7.1%, P>0.05). No statistical difference was noticed in the efficiency between the HFR group and the CFR group (P>0.05). The efficiency in patients with lymph node metastasis at diameters ≤2 cm was significantly higher than that with lymph node metastasis at diameters >2 cm (P<0.05). The median overall survival (OS) of the HFR group showed a significant increase compared with that of the CRF group [24.2 months (95%CI 16.2-32.1 months) vs. 11.8 months (95%CI 9.2-14.4 months)] (χ2=5.063, P<0.05). Both univariate and multivariate analysis indicated that TGLN diameter (P<0.05) and fractioned types (P<0.05) were factors that affected the prognosis.@*Conclusions@#The combination of HFR and chemotherapy contributed to the improvement of prognosis in EC patients with TGLN metastasis and there was no obvious increase in the adverse events.@*Trial registration@#Chinese clinical trial registry, ChiCTR1800016848

Investigation and research in self-congruence characteristic of nurses in military hospitals / 中国实用护理杂志

Objective To understand the state of self-congruence in nurses and discuss their rela-tion with psychological health. Methods Self coasisteney and congruence scale (SCCS) and state-trait anxiety inventory (STAI)were used to test 216 nurses. Results The degree of self-congruence of nurses was relatively low,difference existed in self-congruence among nurses in different departments (P<0.05). Self-congruence was significantly related with state-trait anxiety(P<0.01). Conclusions Selective psy-chological intervention needs be given to some nurses to maintain their psychological health.