Effect of salicylates on gentamicin ototoxicity in humans

Reports showed a protective effect of salicylates, when given in low doses, against Gentamicin-induced ototoxicity in animals. The aim of the present study was to test this contention in humans. The study included 30 patients recruited from the chest department. Fifteen patients served as control and took Gentamicin, for 10 to 14 days. The study group included 15 patients taking the same dosage of Gentamicin in addition to aceryl salicylic acid. Audiologic evaluation was done in the form of pure tone audiometry, transient-evoked and distortion product [DP] oto-acoustic emission. The evaluation was done before the start of therapy and immediately after its cessation. In the study group, salicylates resulted in significant protection of outer hair cells against gentamicin-induced ototoxicity, which was manifested by the following: 1-Improved reproducibility of the transient emissions, although levels of emission decreased. 2-Increased DP peak levels. 3-Improved DP thresholds. 4-Increased DP levels-at-thresholds. The study recommended the use of salicylates as an adjuvant to Gentamicin to reduce the latter's ototoxic effects

Relationship of obesity to the course of labour and delivery among Egyptian obese pregnant women

The aim was to study the effect of obesity on the course of labor and delivery among Egyptian pregnant mothers. Tools of data collection included modified Garow's scale of obesity, admission sheet, and partogram. Subjects were followed up starting from admission and through the 4 stages of labor. Results revealed that the obese group had different demographical characteristics from the non-obese. However, the different was not significant. Also, the obese group had more diseases during previous labor and deliveries than the non-obese. The course of labor and delivery differed significantly between the 2 study groups. The obese group was found to have a mean duration of labor that was significantly longer than that of the non-obese. The 2 groups differed significantly in relation to the duration of the first, second, and third stages of labor, with the obese group having longer mean of duration of each stage. Moreover, the obese group had more significantly cesarean deliveries than the non-obese and also had higher rate of complications related both to labor and delivery such as premature rupture of membrane [PROM] and postpartum bleeding [4 the stage of labor]

Maternal behaviors and initial maternal-infant interaction of the vaginally and cesarean delivered mothers

This study investigates the maternal behaviors and the initial-infant interaction of the vaginally [v/D] and Cesarean [C/S] delivered mothers. Concepts from mother-infant attachment theory were used as theoretical framework. Subjects [N=28] were Egyptian women who had normal vaginal [N=14] and cesarean [N=14] deliveries and their newborn infants. Each subject in both groups was observed in the 2nd day postpartum for a period of three hours, with a total of 84 hours of participant observation. An observation sheet developed by the investigators was used. Major items included were: maternal physical and social behaviors and initial maternal-infant interaction. To compare between the two groups in relation to maternal behaviors and initial mother-infant interaction, results were analyzed quantitatively and qualitatively. Findings pertained to physical behavior revealed that feeding represented 66% of all physical behaviors among V/D group compared to 63% among C/S group. Sixty-five% of feedings in V/D group were carried out when the infant was not crying compared to 37% among C/S group. Mean time lapse before initiation of feeding behavior was 5.7 minutes for V/D versus 13 minutes for C/S. Mean duration for feeding behavior was 4.5 minutes for V/D compared to 7.7 minutes for C/S. Time lapse before initiation of changing diaper and cleaning behaviors was 4 minutes for V/D versus 20 minutes for V/D versus 20 minutes for C/S. Qualitative analysis of data revealed that maternal-infant interaction differed between mothers with V/D and C/S. Mothers with V/D showed "Eager" maternal- infant interaction, and high concern about infant's wellbeing and high concern about self. Pain, infants's condition at birth, and infant's sex were found to be constraints for showing maternal behaviors amoung C/S mothers. It was concluded that maternal behaviors and initial interaction of mothers with their newborn infants differed between mothers with V/D and those with C/S

Effect of application of ice packs to the perineum on the peeling of pain and degree of edema

Two identical groups of post-partum mothers [an experimental and control] 17 subjects each were studied in relation to effect of ice on relieving pain and minimizing ederna of perineum one hour after delivery. Significant difference was found between the two groups in relation to pain and edema

effect of lecture demonstration method on students' clinical performance in maternity nursing course

It was obseved that nursing courses in general and maternity coursed specifically are of unique nature i.e. it needs a combination between the different teaching methods that the teacher can use. The purpose of this study was to evaluate different methods of teaching in order to measure their effectiveness and validity on student's performance both for gaining knowledge and psychometer skills.The sample included two groups of nursing students at the department of maternal and newly born health nursing, High Inst. of Nursing, Cairo Univ. They were exposed to two methods of teaching [lecture demonstration and bedside demonstration]. Both the scores of clinical evaluation, mid-term and final examinations were used to measure the effectiveness of those methods that were previously mentioned.No statistical difference was observed between both the control and experimental groups