Chinese Herbal Medicine and Liquid Wax for the Treatment of 30 Patients with Apatinib-induced Hand-foot Syndrome / 上海针灸杂志

Objective To investigate the clinical efficacy of Chinese herbal medicine and liquid wax in treating oral apatinib-induced hand-foot syndrome. Method Thirty patients with gastric or gastroesophageal junction adenocarcinoma, who had developed hand-foot syndrome after oral administration of apatinib for four weeks, with grade 0 in 3 cases, grade Ⅰ in 16 cases, grade Ⅱ in 9 cases and grade Ⅲ in 2 cases, were enrolled and treated by external application of Chinese herbal medicine and liquid wax on both hands and feet for three weeks. Result The 30 patients with hand-foot syndrome had grade 0 in 14 cases, grade Ⅰ in 14 cases, grade Ⅱ in 2 cases and grade Ⅲ in 0 case after treatment with Chinese herbal medicine and liquid wax. There was a definite therapeutic effect and a statistically significant difference (P<0.05). Conclusion External application of Chinese herbal medicine and liquid wax on both hands and feet for hand-foot syndrome not only has a definite therapeutic effect but is also an ideal means of prevention and treatment because of its noninvasive procedure and the high compliance of the patients.

Observations on the Efficacy of Transcutaneous Electrical Acupoint Stimulation plus Acupoint Pressing in Treating Headaches After Paranasal Sinus Surgery / 上海针灸杂志

ObjectiveTo investigate theefficacy of transcutaneous acupoint electrical nerve stimulation plus acupoint pressing in treatingheadachesafter ethmoidectomyforchronic nasosinusitis.MethodOne hundred patients withchronic nasosinusitiswho hadundergoneethmoidectomyunder general anesthesia were randomly allocated to treatment and control groups, 50 cases each.The control group received routine treatment (auricular plastertherapy,anti-inflammatoryandhemostatic therapy, andoxygen uptake) and the treatment group, transcutaneous acupoint electrical nerve stimulation plus acupoint pressing in addition.Postoperative headache severities were comparedbetweenthe two groups at 6, 12 and 24 hrs after thebeginningof treatment.ResultHeadaches were relieved more significantly in the treatment group than in thecontrol groupat 6, 12 and 24 hrs, especially at 24 hrs. ConclusionsTranscutaneous acupoint electrical nerve stimulation plus acupointpressing has a marked therapeutic effect on headachesafter paranasal sinus surgeryand cansignificantlyimprove postoperative quality of life in the patients.This treatment is non-invasive and more easily accepted by the patients and canimprovethe operatingefficiency and feasibility.