A Case of Newly Found Lymphoepithelial Carcinoma in Retropharynx of the Patient Who Had Been in the NED State of Nasopharyngeal Carcinoma: Controversy about the Recurrence of Undiffentiated Nasopharyngeal Carcinoma / 대한이비인후과학회지

Lymphoepithelial carcinoma is a rare subtype of head and neck malignancy. Histologically, it is an undifferentiated carcinoma accompanied by a prominent reactive lymphoplasmacytic infiltrate. We report a case of anewly found lymphoepithelial carcinoma in the retropharynx of a patient who had been diagnosed and treated as nasopharyngeal carcinoma with multiple metastasis; the case could not be ruled out as a recurrence of nasopharyngeal carcinoma according to recent World Health Organization pathology guideline.

A Case of Newly Found Lymphoepithelial Carcinoma in Retropharynx of the Patient Who Had Been in the NED State of Nasopharyngeal Carcinoma: Controversy about the Recurrence of Undiffentiated Nasopharyngeal Carcinoma / 대한이비인후과학회지

Lymphoepithelial carcinoma is a rare subtype of head and neck malignancy. Histologically, it is an undifferentiated carcinoma accompanied by a prominent reactive lymphoplasmacytic infiltrate. We report a case of anewly found lymphoepithelial carcinoma in the retropharynx of a patient who had been diagnosed and treated as nasopharyngeal carcinoma with multiple metastasis; the case could not be ruled out as a recurrence of nasopharyngeal carcinoma according to recent World Health Organization pathology guideline.

Clinical Characteristics of Benign Oral Cavity Tumors: A Single-Institution Retrospective Study of 257 Patients / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: The study aimed to analyze the histopathologic types and clinical characteristics of benign oral cavity tumors and to identify their possible etiologic factors. SUBJECTS AND METHOD: This was a 10-year retrospective analysis of histologically diagnosed benign tumors in the oral cavity. Data was compiled for each case, documenting information about gender, age, habits (smoking and alcohol), characteristics of the lesion (site, size, color, surface and consistency), comorbidities and denture. RESULTS: Of 257 pathologically confirmed cases of excisional biopsies, the most prevalent were in the order of mucocele (47.08%), fibroma (14.79%), and hemangioma (9.34%). Labium (50.19%) and oral tongue (22.18%) were among the most frequently affected sites. In this study, there was a significant female predominance in fibroma and granuloma. On comparing the mean age of the patients for the different types of tumors, we found that mucocele had the lowest age and that there is a similar mean age among the tumors. The vast majority (99.2%) was represented by non-ulcerated masses and only 2 (0.8%) were ulcerative masses. With respect to habits, we found no significance between comorbidities and denture. CONCLUSION: Based on this study, we can state that while mucocele is the most frequent benign tumor of the oral cavity, labium is the most frequently affected site. The mean age of the patients is lowest for mucocele, and there is a high prevalence of fibroma and granuloma occurring among females. However, with respect to habits, we found no significance between comorbidities and denture.

The Impact of Thyroid Nodule Size and Fine-Needle Aspiration Biopsy Result on the Risk of Malignancy in the Patients Who Underwent Thyroidectomy / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: The frequency of ultrasonography and cytological examinations for thyroid nodules has increased. But the efficacy of fine needle aspiration biopsy varies according to the size of the nodules. The study aimed to identify the effect of thyroid nodule size on malignancy. SUBJECTS AND METHOD: The medical records of patients who underwent total or hemithryoidectomy in a single tertiary hospital were retrospectively analyzed. A total of 204 nodules were obtained from 193 patients who underwent fine needle aspiration biopsy before thyroid surgery. After each nodule was classified by size, the results of the fine needle aspiration test and risk of the final diagnosis were evaluated using logistic regression analysis. RESULTS: The average size of 204 Bethesda class 2 (benign) nodules was 2.99 cm, which was larger than those of other classes (p<0.05). In the final histopathologic diagnosis, there was a difference in size between benign (2.41 cm) and malignant nodules (1.23 cm) (p<0.05). In addition, a logistic regression analysis showed that the nodules below 2.0 cm in size showed an odd ratio of 7.81, compared to the nodules larger than 2.0 cm (p<0.05). CONCLUSION: According to the results of this study, malignancy was higher when the thyroid nodule was less than 2 cm. Therefore, a careful observation is needed for nodules less than 2 cm for which fine needle aspiration biopsy would be recommended. Conversely, it is necessary to reconsider the diagnostic surgery for nodules larger than 2 cm.