Management of ventricular arrhythmias in pregnancy / 中国实用妇科与产科杂志

Ventricular arrhythmias in pregnancy is a common disease of cardiovascular disease during pregnancy which can cause adverse outcomes in severe state,such as maternal heart failure,sudden death,fetal hypoxia,premature delivery and stillbirth.The management of ventricular arrhythmias requires multidisciplinary participation,including obstetrics,cardiology,anesthesiology and neonatology.This article discusses how to manage the ventricular arrhythmias from the following aspects:pre-pregnancy counseling and assessment,treatments,managements during pregnancy and managements of delivery in order to reduce the occurrence of maternal and fetal complications,and emphasizes the significance of multidisciplinary collaborative management to the prognosis of disease.

Clinical research of iron protein succinate on treatment of pregnant iron deficiency anemia / 中国实用妇科与产科杂志

OBJECTIVE:To evaluate the efficacy and safety of proteinsuccinic iron oral liquid on treatment of irondeficiency anemia in pregnant women by using polysaccharide iron complex as a control drug.METHODS:A total of 28724-28 weeks pregnant women that were diagnosed of IDA were randomly selected from six qualified Grade Ⅲ Ahospitals in Sichuan Province,Shaanxi Province,Guangdong Province,Shandong Province,and Jiangsu Province in2016. 144 cases were randomly Assigned in the control group and 143 cases in the test group. After 2 weeks and 4 weeksof treatment,various efficacy and safety indicators were detected and recorded.RESULTS:The improvement rate ofhemoglobin at 2 weeks and 4 weeks after treatment in the study group were 31.43% and 15.89%,respectively,which werehigher than 7.19% and 3.05% of the control group(P0.05). There was no significantdifference in the incidence of adverse reactions between the two groups(P>0.05).CONCLUSION:Protein iron succinateoral solution has less adverse reactions,easy absorption,good taste,and has a good therapeutic effect on pregnant irondeficiency anemia.

Analysis of the perinatal outcome of the early severe preeclampsia women treated with Compound Danshen Injection and low molecular weight heparin / 中国中西医结合杂志

<p><b>OBJECTIVE</b>To study the effects of using Compound Danshen Injection (CDI) and low molecular weight heparin (LMWH) on early severe preeclampsia women.</p><p><b>METHODS</b>Retrospective analysis was carried out in 95 patients with early severe preeclampsia from October 2008 to January 2011. They were assigned to 3 groups based on anticoagulant drugs. The routine therapy of magnesium sulfate (MgSO4) was given to the MgSO4 group (40 cases); the MgSO4 + CDI was given to those in the CDI group (23 cases), the MgSO4 + LMWH group was given to those in the LMWH group (32 cases). The general data of all patients were collected to analyze their effects on labor, postpartum hemorrhage, reasons for terminating the pregnancy, and maternal complications.</p><p><b>RESULTS</b>(1) The average gestational week (weeks) of terminating the pregnancy was 31.7 +/- 1.9 in the MgSO4 group, 33.0 +/- 1.8 in the CDI group, and 32.8 +/- 1.7 in the LMWH group. The average weight of newborn babies (g) was 1 450.5 +/- 402.3 in the MgSO4 group, 1 582.2 +/- 332.5 in the CDI group, and 1 590.0 +/- 340.1 in the LMWH group. There was no obviously difference in the average gestational weeks or the average weight of newborn babies among the three groups. (2) The way of terminating the pregnancy was uterine-incision delivery. The main reasons for operation were sequenced as maternal complications, unsatisfied control of the blood pressure, and fetal distress. (3) The maternal complications in the three groups were sequenced as renal failure (12 cases), placental abruption (9 cases), hemolysis, increased liver enzymes and low platelet (HELLP) syndrome (8 cases). Sixteen (40.0%) had complications in the MgSO4 group, 12 (52.2%) in the CDI group, and 15 (46.9%) in the LMWH group. No statistic difference existed among the 3 groups.</p><p><b>CONCLUSIONS</b>LMWH and CDI were helpful to improving the therapeutic effects of severe preeclampsia patients. They did not increase adverse drug reactions. They seemingly had effects on prolonging the gestational week.</p>

Study on prevalence and risk factors of sleep disorder among Chinese children aged 0 to 23 months in city / 中华预防医学杂志

<p><b>OBJECTIVE</b>To investigate the prevalence and main influences on sleep disorder among Chinese children aged 0 to 23 months, as to providing scientific interventions for infant sleep disorder.</p><p><b>METHODS</b>All 7601 children under two years old were selected by stratifying samples from twelve cities in China. The objects' parents were surveyed with questionnaire. All data were analyzed with SPSS statistical software.</p><p><b>RESULTS</b>The total incidence of sleep disorders at 0 to 23 months was 21.94%. The main problems were difficulty falling asleep, nighttime waking and snoring. Feeding manner, sleep environment, sleep-associated habits and medical conditions were all influences on infant's sleep disorder.</p><p><b>CONCLUSIONS</b>Enhancing sleep health education to change parents' nurturing modes should be an important role in preventing infant sleep disorders.</p>

The interaction between microsomal epoxide hydrolase polymorphisms and indoor pollution in non small cell lung cancer / 中华预防医学杂志

<p><b>OBJECTIVE</b>To determine the interaction between indoor air pollution and mEH gene polymorphisms.</p><p><b>METHODS</b>Blood samples from 222 non small cell lung cancer patients and 222 healthy people were characterized by PCR and PCR-RFLP methods. The interaction coefficients were determined through unconditional logistic regression model.</p><p><b>RESULTS</b>Significant differences in the positive rate of mEH-exon3 mutant and the heterozygote were found between case and control groups (chi(2) = 7.046, P = 0.030). But no significant difference was found in mEH-exon4 non-wild-type between groups (chi(2) = 2.674, P = 0.263). mEH-exon3 mutant (OR = 1.99; 95% CI = 1.21, 3.25) could significantly increase the risk of lung cancer. After adjusted by confounding variables, significant interactions were found between the use of coal-wall stove and the non-wild type mEH gene. The interaction coefficients were increased with the duration of exposure and quantity of coal consumed. The super multiplication models were established between non-wild type mEH gene and the exposure to soot or oil fume during cooking. The interaction coefficients were 2.75 and 7.34 respectively for exon3 and exon4. No interaction was found between non-wild type mEH gene and irritation of eye or throat during cooking.</p><p><b>CONCLUSION</b>Through the molecular epidemiological techniques, we confirmed indoor air pollution that caused by coal burning was a noticeable lung cancer risk factor. The interaction between the polymorphisms of mEH gene and the indoor air pollution plays an important role in the carcinogenesis of lung.</p>