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AIM To investigate the effects of Sanqi Huayu Oral Liquid (Notoginseng Radix et Rhizoma,Corydalis Rhizoma) on femoral shaft comminuted fracture caused by trauma in perioperative period of high-risk groups.METHODS One hundred and twenty patients meeting the inclusion criteria were randomly and equally divided into treatment group and control group.The control group was treated by low molecular weight heparin calcium injection,while the treatment group was additionally given Sanqi Huayu Oral Liquid.Two groups' levels of serum IL-6,TNF-α and D-D were detected on pre-operation and the 1 st,3rd,7th after operation,respectively.Additionally,the adverse drug reactions were also observed.RESULTS There were no statistically significant differences in the levels of serum IL-6,TNF-α and D-D between the two groups before operation.The first day after operation,the levels of serum IL-6,TNF-α and D-D between the two groups showed increasing trends,which had similar elevated levels without statistically significant differences.The third day after operation,the levels of serum IL-6,TNF-α and D-D between the two groups presented downward trends,but those in the treatment group were decreased more markedly with statistically significant differences.Furthermore,the seventh day after operation,the levels of serum IL-6,TNF-α and D-D between the two groups were lower than those before the operation,and these indices in the treatment group were lower than those in the control group with statistically significant differences.CONCLUSION Sanqi Huayu Oral Liquid can not only effectively reduce the levels of serum IL-6,TNF-α and D-D in perioperative period of high-risk groups,but also prevent the formation of deep vein thrombosis.
RESUMO
Objective To observe the clinical effect of traditional Chinese medicine fumigation combined with rehabilitation exercise on the recovery of elbow joint function after triad disease of elbow joint. Methods Sixty patients with terrible triad disease of elbow were divided into treatment group and control group according to the random number table. The treatment group was treated with traditional Chinese medicine fumigation combined with rehabilitation exercise. The control group was treated with rehabilitation exercise. The clinical effect rates, elbow activity and De Boer YA elbow function score were observed at 4 weeks and 8 weeks after treatmentt. Results The total effect rate was 83.3% (25/30) in the treatment group and 60.0% (18/30) in the control group, and the difference between the two groups was statistically significant (χ2=4.021, P=0.044).After treatment,the elbow flexion(126.98 ± 10.46°vs.120.86 ± 10.37°,t=2.275),the hyperextension (8.26 ± 1.23° vs. 6.79 ± 1.29°, t=4.517), pronation (80.46 ± 8.60° vs. 73.42 ± 8.20°, t=2.404), and supination (78.53 ± 8.26° vs. 73.42 ± 8.20°, t=2.404) in the treatment group were significantly higher than those in the control group.. The De Boer YA elbow function score pain (27.13 ± 2.56 vs. 24.86 ± 2.42, t=3.529), Daily activities (32.26 ± 4.24 vs. 29.48 ± 4.36, t=2.503), movement (31.46 ± 4.66 vs. 28.74 ± 4.59, t=0.026), total score(90.42 ± 8.76 vs.83.82 ± 8.42,t=2.975)in the treatment group were significantly higher than those in the control group (Ps<0.05). Conclusions Traditional Chinese medicine fumigation combined with rehabilitation exercise can promote the recovery of elbow joint function in triad of elbow joint.