The efficacy of intratympanic dexamethasone injection for the moderate and severe sudden deafness with BPPV / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To evaluate the efficacy of intratympanic dexamethasone injection for the moderate and severe sudden deafness with BPPV.@*METHOD@#A total of 63 patients diagnosed with sudden sensorineural hearing loss with BPPV were treated through OPD. Patients were divided into three groups: 20 cases in intratympanic dexamethasone injection as initial treatment (group A); 18 cases in systemic hormone therapy group (group B); 25 cases in intratympanic dexamethasone injection as salvage treatment (group C). In addition, routine drugs were used to all patients.@*RESULT@#The overall effective rate of group A, B and C in hearing recovery was 60.0%, 38.9% and 48.0%, respectively: (1) No significant difference of hearing recovery was observed among three groups (P > 0.05); (2) A significant difference of hearing recovery was evidenced between group A and C (P 0.05).@*CONCLUSION@#Our data showed that intratympanic dexamethasone should be used as initial therapy for treating the moderate and severe sudden deafness with BPPV.

The preliminary research of progress on sudden deafness with benign paroxysmal positional vertigo patients / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To investigate the prognosis of sudden deafness patients with benign paroxysmal positional vertigo (BPPV).@*METHOD@#The clinical data of 24 sudden deafness patients with BPPV was analyzed. The outcome of 125 sudden deafness patients without BPPV at the same time was compared.@*RESULT@#Hearing improvement after three months treatment was 41.67% and 72.80% in sudden deafness patients with BPPV and sudden deafness patients without BPPV, respectively. The difference was statistically significant (P<0.05).@*CONCLUSION@#The prognosis of hearing in sudden deafness patients with BPPV is worse than that in sudden deafness patients without BPPV. BPPV may predict a poor hearing outcome in sudden deafness.

Therapeutic Efficacy of High- dose Methylprednisolone plus Batroxobin Injection for Sudden Deafness / 中国药房

OBJECTIVE:To evaluate the therapeutic efficacy of high-dose Methylprednisolone plus Batroxobin Injection for sudden deafness(SD).METHODS:62 SD cases(66 ears) were randomly assigned to receive conventional therapy alone (control group,32 cases/34 ears) or conventional therapy in combination with high - dose Methylprednisolone(trial group,n= 30 cases/32 ears) for 12 days.The clinical efficacy was compared between the two groups.RESULTS:The total effective rate of the trial group vs.the control group was 93.75%vs.76.47%(P