RESUMO
Objective To study the prevalence of human papillomavirus(HPV) infection and type-distribution of 21 common types in the cervix of female residents in Zhengzhou.Methods Female residents in Zhengzhou at age of 18 or older were voluntarily enrolled in the study.Real-time fluorescent quantitative-PCR was applied to do the cervical HPV screening test and geno-typing.Results Of the 50502 cases,4740 were HPV positive,which including 78/912 (8.55％) at age of 18 to 30,1042/11608(8.98％) at age of 31 to 40,2217/24500(9.06％) at age of 41 to 50,1401/23482 (10.39％) at age of ＞ 50.The overall prevalence of HPV infection was 9.39％ (4740/50502).Among the HPV positive cases,prevalence of high-risk-HPVs (HR-HPVs) and low-risk-HPVs (LR-HPVs) were 8.88％ (4485/50502) and 1.08％ (534/50502) respectively.Of those 21 types of HPV,HPV 52 was the most common HR-HPV accounting for 20.99％ (995/4740),HPV 16 was the next one,accounting for 7.66％ (363/4740),HPV 58 was the third leading infection accounting for 13.73％ (651/4740).Among LR-HPVs,the most common was HPV 81 accounting for 7.66％ (363/4740),and the next one was HPV 6 accounting for 2.78％ (132/4740),HPV 11 was the third one accounting for 1.08％ (51/4740).There were 1532 of multi-infections accounting for 32.32％ (1532/4740).Of multi-infections,there were 989 of double-infections,275 of triple-infections,71 of quadruple-infections,20 of quintuple-infections,and 3 of sextuple-infections.Of all different double-infections,HPV 52 + HPV58 was the most common combination.Conclusion Compared and analyzed with other HPV epidemiological survey results in China,the prevalence of HPVs in Zhengzhou city was at low level nationally which was going up with age gradually.However,the risk to get multiple HR-HPV infections increased significantly if people were older than 50.The leading three HPV types were HPV-52,16 and 58.
RESUMO
Objective To explore the rule of traditional Chinese medicine in treating tinnitus based on literature and Logistic multiple regression analysis. Methods Articles about tinnitus treatment using traditional Chinese medicine were searched in several databases, i.e. CNKI (1984-2013), VIP (1989-2013), CBM (1990-2013), and PubMed (1984-2013), and medication frequency was analyzed. Then, models for tinnitus medication were established through metrological method and Logistic multiple regression. Results The common prescriptions with highest frequency usage were Liuwei Dihuang Pill, Longdan Xiegan Decoction, and Erlong Zuoci Pill. Corni Fructus, Psoraleae Fructus, and Lycii Fructus were commonly used for kidney-deficiency type of tinnitus;Astragali Radix, Atractylodis Macrocephalae Rhizoma, and Codonopsis Radix were commonly used for the spleen-qi-deficiency type of tinnitus;Gardeniae Fructus, Gentianae Radix et Rhizoma, and Cyperi Rhizoma were commonly used for the liver-qi-dysfunction type of tinnitus;Pinelliae Rhizoma, Aurantii Fructus Immaturus, and Stephaniae Tetrandrae Radix were commonly used for the phlegm-fire disturbance type of tinnitus;Forsythiae Fructus, Menthae Haplocalycis Herba, and Mori Cortex were commonly used for the wind-fire-invasion type of tinnitus. Conclusion Analysis of medication frequency and Logistic multiple regression analysis can provide evidence and reference for the treatment of tinnitus and syndrome differentiation.