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Objective@#To evaluate the non-carcinogenic health risk of heavy metals (As, Cd, Cr, Cu, Mn, Pb and Zn) in residential indoor dust for young children around an e-waste dismantling area in South China.@*Methods@#A village around an e-waste dismantling area in South China was selected as a research site in October 2016. Convenience sampling method was used to select 36 houses in the village and 36 dust samples were collected by vacuum cleaner. The concentrations of heavy metals (Cd, Cr, Cu, Mn, Pb and Zn) in each sample were determined and expressed by the average value. Non-carcinogenic health risk assessment was conducted using the US Environmental Protection Agency (EPA) Health Risk Assessment (HRA) model, the American Toxicology and Disease Registry (ATSDR) Target-organ Toxicity Dose (TTD) approach and the ATSDR Binary Weight-of-Evidence (BINWOE) model.@*Results@#The mean ± SD of concentrations of As, Cd, Cr, Cu, Mn, Pb and Zn were (48.90±33.91), (5.95±3.89), (173.57±580.37), (412.71±1 190.00), (612.82±540.70), (297.41±293.22) and (1 052.81±1 156.48) mg/kg, respectively. The HI value of TTD (2.670) and BINWOE (2.933) were higher than the safety threshold of EPA recommended non-carcinogenic health risk. The HI value of TTD and BINWOE were 1.93 and 2.12 times higher than the HI value of HRA (1.386).@*Conclusion@#There was non-carcinogenic health risk of heavy metals (As, Cd, Cr, Cu, Mn, Pb and Zn) via residential indoor dust around the e-waste dismantling area for local children.
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Objective To investigate the effects of pollution on nonspecific immune function of the children living nearby a municipal solid waste landfill.Methods The concentration of lysozyme and SIgA of saliva came from 951 children who were selected from 3 schools nearby the landfill were analyzed by cluster sampling while the outside air pollutants were detected in 2006.The high-exposure group included 360 students living in a radius of less than 2 km from the landfill,the low exposure group was consist of 361 students living in a radius of 2-5 km,the others 230 students living in more than 5 km were taken as the control group.Results The results showed that the pollutants levels were concerned with the location of the landfill,the nearer to the landfill,the higher concentration of CH4,NO2,SO2,NH3,H2S and PM10 except CO.The level of saliva lysozyme ranked as high exposure group,low exposure group and the control group were 61.40,71.37 and 76.10 ?g/ml and the same rank for SIgA were 204.11,224.28,248.44 ?g/ml,with significant differences (P
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More and more attentions have been paid to the harm of environmental arsenic pollution to human health.The mechanism of arsenic metabolism in human body was described,the interaction mechanism and research advance were reviewed in the present paper,including the damages to skin,digestive system,urinary system,immune function,nervous system,cardiovascular system,respiratory system and inheritance system.It is useful not only to enhance understanding for the relation between arsenic pollution and health damage,but also to provide the basic theory to control the arsenic pollution.The present paper also made suggestions in the future research in this field.
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Cr. The potential ecological risk index of the whole regions had reached the middle level,and that of Hg had already reached the degree of strong hazard. Conclusion The long-term sewage irrigation has caused serious heavy metals pollution in the soil of irrigation regions.
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Electronic waste (E-waste) arising from the rapid development of high-tech industries such as electronic information has become the fastest-growing solid waste,its impact on the environment and health aroused more and more people’s concern. The progress on the study of E-waste on the environment and human health was reviewed in this paper,the limitation of current researches and the future direction were also analyzed and assessed.
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With the development of systems biology and high-throughput molecular technologies, systems toxicology has come into being. The up-date understanding of systems toxicology is the study of the perturbation of biological systems by using chemicals and stressors, monitoring changes in molecular expression (transcript, protein and metabolite profiling), conventional toxicological parameters and iteratively integrating response data to describe the functioning organism. The background, research framework, supporting tools and the main applications of systems toxicology were discussed in detail in the present paper. Although in its infancy, systems toxicology will play an important role in advancing the study of environmental stress and heath impact definitely.