Guidelines for Ideological and Political Teaching of the Doctor-patient Communication Courses / 中国医学伦理学

To promote the ideological and political construction of the doctor-patient communication course, the research group discussed the subject characteristics and proposed the goals, principles, elements, and paths of the ideological and political construction of the doctor-patient communication course combined with practical teaching and relevant policy documents. Besides, this paper put forward the top-level framework design for the implementation, curriculum assessment, and evaluation indicators of the ideological and political construction, and developed the Guidelines for Ideological and Political Teaching of the Doctor-patient Communication Course and related teaching evaluation indicators, with a view to providing reference evaluation standards for the ideological and political construction of the doctor-patient communication course in China.

Study on binding capacity of low-density lipoprotein to its receptors in diabetic patients / 中华内分泌代谢杂志

The levels of low-density lipoprotein(LDL)glycation from control group,diabetic HbA1C 7.0% groups were(17.7±2.31),(34.29±5.73),and(48.79±7.82)Glycogroups/LDL by fluorimetry.The LDL binding to its receptor in three groups were(37.65±5.20),(27.36±4.34),and(15.07± 2.23)ng/mg cell protein measured by enzyme-linked immunoreceptor assay.The glycated levels in two diabetic groups were higher than that in control group,and higher in HbA1C>7.0% group than in HbA1C<7.0% group(all P< 0.01).The results of LDL binding capacity to its receptor were just the opposite.

The localizing analysis of the moral status of the embryo in secular bioethical view / 中华医学教育探索杂志

The discussion of the moral status of the embryo mainly focuses on the debating of human beings and human persons in western country.From the angle of the localizing view,the embryo is not a real person.The abortion can get defended.Considering the embryo has potential and value relationship,it has the limited moral status.In dealing with the problem,we should not protect the embryos by emphasizing the embryo's moral position,but we should control abortion appropriately by humanitarian perspective to respect the embryo.

Study on a pedigree with Leydig cell hypoplasia caused by novel mutation of luteinizing hormone receptor / 中华内分泌代谢杂志

Objective To investigate a Chinese pedigree suffering from Leydig cell hypoplasia ( LCH) based on clinical data and genetic diagnosis. Methods The patient was diagnosed by means of clinical data, hormone profiles, and human chorionic gonadotropin ( hCC) test. The luteinizing hormone/chorionic gonadotropin receptor(LHCGR) gene of the patient and family members was amplified and sequenced. Results The patient presented with male pseudohermaphroditism, low level of testosterone, which did not respond to hCG. Genetic analysis of the LHCGR revealed two novel mutations: a missense mutation located in exon 5, resulting in Ile replaced by Thr in the extracellular domain; and a splice site mutation in the 3' terminal of intron 6( IVS6-3 C→A). Proband's sister (46, XX) who lacked clinical manifestations showed the identical genotype with the patient. Conclusions A mutation in the consensus sequence of 3' splice site, in addition to a missense mutation (Ile 152Thr)in the extracellular ligand-binding domain is the cause of inactivation of the LHCGR gene in patient with Leydig cell hypoplasia.

The curriculum of reformation of the ideology, moral culture and the basis of law in medical college should be inosculated into the medical humanities / 中华医学教育探索杂志

Medical humanities teaching in medical college can not been taken on by single or several curriculums,and should be inosculated into all of the medical teaching taches.The curriculum of ideology,moral culture and the basis of law(shortened form to basis) is the required course prescribed by the national education department for all the freshmen. The curriculum reform of the basis should be combined with the characters of the medical circumstances, inosculated into the medical humanities,and should become an important platform of the medical humanities educating system.

The Humanities Ideas of Medicine and Several Propositions on Humanities Education in Medical Universities / 中国医学伦理学

As a branch of natural science,medical science also contains abundant humanities ideas.'Medicine is a human course' and 'medicine is a kind technology ' embody the humanity evaluation of medical science from western and Chinese cultural history of medical science respectively.The humanities education in medical universities should take the medical science humanities spirit as educational principle,and pay attention to the course design,teacher installment,instructional reform,and evaluating system.

Chemical constituents of Melastoma dodecandrum(Ⅱ) / 中草药

Objective To study the constituents in Melastoma dodecandrum.Methods The constituents were isolated by chromatographic methods,and their structures were elucidated by spectroscopic evidences.Results Five compounds were purified and their structures were identified as: daucosterol(Ⅰ),oleanolic acid(Ⅱ),avicularin(Ⅲ),3,7,4′-trimethoxyquercetin(Ⅳ),and atractylenolidone(Ⅴ).Conclusion Compound Ⅴ is a new chemical constituent named atractylenolidone.Compound Ⅳ is isolated from M.dodecandrum for the first time.