RESUMO
Objective To explore the clinical effects on endoscopic treatment of chronic pancreatitis (CP) and the improvement of the symptoms of patients with abdominal pain, to provide basis for clinical treatment. Methods 81 patients with CP treated by endoscopic were selected from July 2011 to June 2013. Observe the efficacy, complications and bellyache. Results The operation of 81 patients were all successful, no death case. 1 week after the average pain was of (2.29 ± 0.14), lower than before the operation (7.13 ± 0.27), the difference was significant (P < 0.05). 1 week after, the operation, painless, mild pain and moderate pain were 46.91% (38/81), 35.80% (29/81) and 13.58% (11/81), were higher than those of preoperation (P < 0.05). The severe pain of after 1 week was 3.70% (3/81), lower than the preoperative 56.79% (46/81) (P < 0.05). 1 week after the operation, fatty diarrhea and malnutrition were 0.00% (0/81) and 7.41% (6/81), were lower than the preoperative 25.93%(21/81) and 37.04% (30/81), the difference was significant (P < 0.05). After 1 week, serum amylase concentration was (74.18 ± 2.75) u/L, was lower than the preoperative (182.45 ± 8.32) u/L, the difference was significant (P < 0.05). Conclusion Endoscopic treatment of chronic pancreatitis was fewer complications, reliable, and with the advantages of minimally invasive and repeated. It was effective in the treatment of patients with chronic pancreatitis and could effectively alleviate the pain.
RESUMO
Objective To explore the clinical effects on endoscopic treatment of chronic pancreatitis (CP) and the improvement of the symptoms of patients with abdominal pain, to provide basis for clinical treatment. Methods 81 patients with CP treated by endoscopic were selected from July 2011 to June 2013. Observe the efficacy, complications and bellyache. Results The operation of 81 patients were all successful, no death case. 1 week after the average pain was of (2.29 ± 0.14), lower than before the operation (7.13 ± 0.27), the difference was significant (P < 0.05). 1 week after, the operation, painless, mild pain and moderate pain were 46.91% (38/81), 35.80% (29/81) and 13.58% (11/81), were higher than those of preoperation (P < 0.05). The severe pain of after 1 week was 3.70% (3/81), lower than the preoperative 56.79% (46/81) (P < 0.05). 1 week after the operation, fatty diarrhea and malnutrition were 0.00% (0/81) and 7.41% (6/81), were lower than the preoperative 25.93%(21/81) and 37.04% (30/81), the difference was significant (P < 0.05). After 1 week, serum amylase concentration was (74.18 ± 2.75) u/L, was lower than the preoperative (182.45 ± 8.32) u/L, the difference was significant (P < 0.05). Conclusion Endoscopic treatment of chronic pancreatitis was fewer complications, reliable, and with the advantages of minimally invasive and repeated. It was effective in the treatment of patients with chronic pancreatitis and could effectively alleviate the pain.
RESUMO
In order to explore the possibility to predict the risk factors for postoperative complications and survival time, the clinical data of 152 patients (including 116 males and 36 females) who had undergone neo-adjuvant therapy and surgery for stage Ilia and B non-small cell lung cancer (NSCLC) were retrospectively analyzed. Demographic data, preoperative functional parameters,staging, induction regimen (chemotherapy alone or associated with radiotherapy), associated disorders, and data about operation were collected. Chi-square test and multivariate analysis fitting the unconditional logistic regression model were performed to identify predictors of postoperative complications, while Kaplan-Meier and multivariate Cox proportional hazard model were employed to identify predictors of survival time, respectively. The univariate analysis demonstrated that forced expiratory volume in 1 second predicted percent (FEVI%, P=0.040) and associated disorders (P=0.020) were the predictive factors of complications, but multivariate analysis found no independence factors (P>0.05) of it. Univariate Kaplan-Meier analysis showed that stage (P=0.050) and pneumonectomy (P=0.018) affected the survival time. However, multivariate Cox proportional hazard model analysis demonstrated that only pneumonectomy (P=0.026) was associated with a decreased survival time, but no differences between right and left pneumonectomy were found. The results suggest that the risk factor for postoperative complications is acceptable, and pneumonectomy is associated with increased mortality, which should be performed only in stage Ⅲ NSCLC patients.