novel synthesis of furocoumarin sulphur analogues

In the present work, a novel method for the synthesis of 7-thiocarboxamidothieno [3',2',6,7] [I] benzopyran-8-one and 8-thiocarboxamidothieno [3',2',6,7] [I] benzopyran-7-one, is reported. The appropriate aldehydes were treated with cyanothioacetamide in presence of triethylamine where the products were subjected to acid hydrolysis to give the desired compounds. The chemical structures of the title compounds and their intermediates were confirmed by studying their spectral data. The biological activity of the prepared furanocoumarin sulfur analogues is under study