A study on the correlation between smoking and non-enzymatic antioxidant factors of the saliva of healthy smokers and non-smokers / Estudo da correlação entre fumo e fatores antioxidantes não-enzimáticos na saliva de pacientes saudáveis fumantes e não fumantes

Objective: Smoking is among the most destructive habits which have numerous effects on the body.The chemical components of cigarettes destroy the anti-oxidant content of the saliva.In this study, the concentration of albumin and uric acid of healthy non-smokers and smokers was measured based on the frequency of smoking. Material and Methods:In this cross-sectional study, 26 heavy smokers, 27 normal smokers, and 29 non-smokers between the ages of 25 to 40 were selected.The subjects did not suffer from any systemic or periodontal conditions.Unstimulated saliva was collected by spitting. The level of salivary albumin was measured by Bromocresol Green, and the level of salivary uric acid was measured by the uricase method.The selected method of analysis, using SPSS software, was One-Way ANOVA. Results: Mean albumin content of saliva was 33.52 ± 1.52 mg/dl in non-smokers and 23.88 ± 8.93 mg/dl in heavy smokers.The mean uric acid concentration in non-smokers was 2.98 ± 0.79 µmol/L and in heavy smokers was 2.32 ± 0.77 mg/dL.The differences between levels of both salivary uric acid and salivary albumin were significant in heavy smokers and non-smokers(P=0.001). Conclusion: Based on the findings of this study, saliva concentrations of both Albumin and Uric Acid change based on the frequency of smoking.Decreased level of salivary albumin and decreased level of salivary uric acid can be considered as markers of the harmful effects of smoking on oral health. (AU)

Objetivo: Tabagismo está entre os hábitos mais deletérios, que causam inúmeros efeitos no organismo. Os componentes químicos do cigarro destroem os compostos anti-oxidantes da saliva. Neste estudo, a concentração de albumina e ácido úrico em pacientes saudáveis fumantes e não-fumantes foi mensurada e correlacionada coma frequência de fumo. Material e Métodos: Neste estudo transversal, 26 fumantes pesados, 27 fumantes moderados, e 29 não fumantes entre 25 e 40 anos foram incluídos. Os participantes não apresentavam nenhuma condição sistêmica ou periodontal. Saliva não estimulada foi coletada. Os níveis salivares de albumina foram avaliados por Verde de bromocresol, e o nível de ácido úrico foi mensurado pelo método de uricase. Os dados foram analisados utilizando-se One-way ANOVA no software SPSS. Resultados: A albumina salivar foi de 33.52 ±1.52 mg/dl nos não-fumantes e 23.88 ± 8.93 mg/dl nos fumantes pesados. A concentração média de ácido úrico em não-fumantes foi de 2.98 ± 0.79 µmol/L e em pacientes fumantes pesados de 2.32 ± 0.77 mg/dL. As diferenças entre os níveis de ambos, ácido úrico e albumina, foi significante entre fumantes pesados e não-fumantes (p=0.001). Conclusão: Baseados nos achados deste estudo, concentrações salivares de albumina e ácido úrico baseados na frequência de fumo. A diminuição dos níveis salivares de albumina e ácido úrico podem ser considerados marcadores dos efeitos nocivos do cigarro na saúde oral(AU)

Association of serum level of 25-hydroxy vitamin D with oral lichen planus: a case-control study / Asociación del nivel sérico de 25-hidroxi vitamina D con el liquen plano oral: un estudio de casos y controles

Introduction: Vitamin D deficiency is a global health problem that can be a risk factor for a broad range of diseases such as some autoimmune diseases. Due to the autoimmune base of lichen planus, it seems that a reduction of the serum level of vitamin D is related to lichen planus. In this study, we investigate the relation between serum level of vitamin D and oral lichen planus patients (OLP). Material and Methods: In this case-control study, 35 patients with OLP (including 15 men and 20 women) and 70 healthy volunteers (including 35 men and 35 women), aged between 30-60 years old, referred to Qazvin University of Medical Sciences were investigated. None of these volunteers had systemic diseases. Vitamin D levels were measured with ELFA (Enzyme Linked Fluorescent Assay) and the data was analyzed using the chi-squared test and t-test. Results: The mean serum level of vitamin D in the control group was 23.7±9ng/ml and in the case group was 18.12±8/7ng/ml. The results show that the serum level of vitamin D in patients with OLP is significantly less than in the control group (p<0.05). Conclusion: According to the results, the serum level of vitamin D in patients with OLP was significantly lower than that of healthy people.

Introducción: La deficiencia de vitamina D es un problema de salud global que puede ser un factor de riesgo para una amplia gama de enfermedades, como algunas enfermedades autoinmunes. Debido a la base autoinmune del liquen plano, parece que una reducción del nivel sérico de vitamina D está relacionada con el liquen plano. En este estudio, investigamos la relación entre el nivel sérico de vitamina D y los pacientes con liquen plano oral (LPO). Material y Métodos: En este estudio de casos y controles, 35 pacientes con LPO (incluidos 15 hombres y 20 mujeres) y 70 voluntarios sanos (incluidos 35 hombres y 35 mujeres), con edades comprendidas entre 30 y 60 años, remitieron a la Universidad de Medicina de Qazvin. Se investigaron las ciencias. Ninguno de estos voluntarios padecía enfermedades sistémicas. Los niveles de vitamina D se midieron con ELFA (ensayo fluorescente ligado a enzimas) y los datos se analizaron utilizando la prueba de chi-cuadrado y la prueba t. Resultados: El nivel sérico medio de vitamina D en el grupo de control fue de 23,7 ± 9 ng / ml y en el grupo de casos fue de 18,12 ± 8/7 ng / ml. Los resultados muestran que el nivel sérico de vitamina D en pacientes con OLP es significativamente menor que en el grupo de control (p<0.05). Conclusión: De acuerdo con los resultados, el nivel sérico de vitamina D en pacientes con LPO fue significativamente menor que en personas sanas.

Factors influencing eruption time of first deciduous tooth / Factores influyentes en el periodo de erupción del primer diente primario

Introduction: Deciduous teeth play an important role in proper growth. Tooth eruption is a complicated process in which different mechanisms are involved. Early or delayed tooth eruption depends on different factors, with the impact of some already established. There are apparent controversy regarding the effect of some factors on time of the first deciduous tooth eruption among the conducted studies. The current study aimed to evaluate factors affecting the time of the first deciduous tooth eruption. Materials and Methods: One hundred and sixty eligible infants referring to the healthcare centers of Tabriz, Iran, were randomly selected; the demographic data including weight and height at birth, head circumference, mother's age and level of education, birth rank in the family and type of feeding were recorded, in addition to the time of the first deciduous tooth eruption. Data were analyzed using SPSS version 21 by ANOVA and t test.Results: Out of 54.1% female and 45.9% male participating infants, 78.3% had normal weight at birth. Results showed a significant relationship between weight at birth and timing of the first deciduous tooth eruption, among the evaluated factors. Conclusions: Although no significant relationship was observed between gender, type of feeding, mother's level of education and birth rank in the family, and time of the first deciduous tooth eruption, there was a significant relationship between the weight at birth and the timing of the first deciduous tooth eruption. Infants with higher or lower abnormal weight at birth had delayed deciduous tooth eruption.

Introducción: los dientes primarios juegan un papel importante en el crecimiento adecuado. La erupción dental es un proceso complexo en el que intervienen diferentes mecanismos. La erupción temprana o tardía de los dientes depende de diferentes factores, con el impacto de algunos ya establecido. Existe controversia entre los estudios realizados con respecto al efecto de algunos factores que afectan la erupción del primero diente primario. El presente estudio tuvo como objetivo evaluar los factores que afectan el periodo de erupción del primero diente primario o temporal. Materiales y Métodos: Ciento sesenta bebés referidos a los centros de salud de Tabriz, Irán, fueron seleccionados al azar; Se registraron los datos demográficos, incluidos el peso y la estatura al nacer, la circunferencia de la cabeza, la edad y el nivel de educación de la madre, el rango de nacimiento en la familia y el tipo de alimentación, además del momento de la primera erupción del diente primario. Los datos fueron analizados por ANOVA y t-test utilizando SPSS versión 21. Resultados: de los lactantes participantes (54,1% femeninos, 45,9% masculinos) el 78,3% tenía peso normal al nacer. Entre los factores evaluados, los resultados mostraron una relación significativa entre el peso al nacer y el momento de la erupción del primero diente primario. Conclusiones: aunque no se observó una relación significativa entre sexo, tipo de alimentación, nivel de educación de la madre y rango de nacimiento en la familia, y el period de erupción del primero diente primario, hubo una relación significativa entre el peso al nacer y el momento de la primera erupción dental decidua. En los lactantes con peso anormal al nacer se había retrasado la primera erupción de los dientes primarios.