Clinical and genetic analysis of a patient with Hb Ottawa in conjunction with β -thalassemia / 中华医学遗传学杂志

OBJECTIVE@#To analyze the hematological characteristics of a patient with Hb Ottawa in conjunction with β -thalassemia.@*METHODS@#Peripheral blood samples from the proband and her parents were collected and subjected to red blood cell analysis and hemoglobin electrophoresis. Genotypes of α - and β -globin genes were also analyzed.@*RESULTS@#The proband and her mother were both heterozygotes for Hb Ottawa and β -thalassemia variant IVS II-654, and presented with typical β -thalassemia trait featuring hypochromic microcytic anemia. An abnormal hemoglobin band was detected upon electrophoresis.@*CONCLUSION@#Co-existence of Hb Ottawa and β -thalassemia may not aggravate the phenotype.

Clinical and genetic analysis of a patient with Hb Ottawa in conjunction with β-thalassemia / 中华医学遗传学杂志

Objective@#To analyze the hematological characteristics of a patient with Hb Ottawa in conjunction with β-thalassemia.@*Methods@#Peripheral blood samples from the proband and her parents were collected and subjected to red blood cell analysis and hemoglobin electrophoresis. Genotypes of α- and β-globin genes were also analyzed.@*Results@#The proband and her mother were both heterozygotes for Hb Ottawa and β-thalassemia variant IVS II-654, and presented with typical β-thalassemia trait featuring hypochromic microcytic anemia. An abnormal hemoglobin band was detected upon electrophoresis.@*Conclusion@#Co-existence of Hb Ottawa and β-thalassemia may not aggravate the phenotype.

Electrocardiography Telemonitoring System for Cardiac Rehabilitation for Myocardial Infarction (review) / 中国康复理论与实践

The electrocardiography (ECG) telemonitoring system is briefly introduced, especially the development progress, including the wearable technology. For early cardiac rehabilitation (CR) after acute myocardial infarction (AMI), the ECG telemonitoring system can monitor heart rate, blood pressure, heart rate recovery (HRR), which is confirmed to assess autonomic nervous function;as well as rate pres-sure product (RPP), which is confirmed to speculate lactate anaerobic threshold during CR, can be calculated to guide the exercise intensity of CR progress. Finally, the legal liability issues if accidents occurred in home-based CR program, and the innovation, such as combining with the network, are discussed.