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Objective To understand the trends and influential factors on infant mortality in Henan province from 2000 to 2010.Methods Descriptive method,Cox-Stuart trend test and multiple linear regression were used to study the infant mortality trends and related influential factors in the regions with monitoring programs of Henan province,fiom 2000 to 2010.Results The total urban and rural infant mortality rates dropped significantly,from 30.91 per thousand,10.05 per thousand,33.99 por thousand in 2000 to 7.12 per thousand,5.51 per thousand,8.03 per thousand in 2010,respectively.The average annual rates of decrease were 13.65 percent,5.83 percent and 13.44 percent.The downward hrends were statistically significant (P＜0.05).The infant mortality rates dropped more significantly in rural areas (25.96％) than in the urban areas(4.54％).Difference between urban and rural areas reduced from 23.49％ to 2.52％.Rates on factors as setting up matemal record cards,carrying on postpartum visits,hospital delivery,or under help by new midwives and low birth weight rate etc.were remarkably influencing the rate on nfant mortality (F=229.738,P=0.004).In order,the inpact of strengths on those factors showed as:hospitalized delivery rate,low birth weight rate,the rate of ‘clean' delivery,setting up record cards on postpartum visits.Conclusion Total provincial,urban and rural infant mortality rates all showed downward trends.The infant mortality rates dropped more significantly in rural areas than in urban arcas.Difference between urban and rural areas was gradually getting small.Rates on setting up maternal record cards,carrying on postpartum visit,hospital delivery and tnder help by new midwives rate were important tactors that significantly impacting the infant mortality rate.Work on setting up record cards and hospital delivery should be further strengthened.
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Objective To investigate the natural history of HIV infection caused by contaminated plasma donation among former commercial plasma donors in China. Methods Ambispective cohort study among HIV/AIDS cases and suspected AIDS deaths was conducted from January 1,1995 to March 31,2008 in 7 administrative villages in Shangcai county of Henan province.Information regarding diagnostic criteria, deaths and anti-retrovirus treatment was collected.Incubation and survival time were calculated using Kaplan-Meier and life-tables method. Sensitive analysis on the time of outcome was conducted. Results A total number of 2569 cases of HIV infection including 483 suspected AIDS deaths were involved in a cohort. 200 patients with rapid progress (7.8%) and 337 long-term but non-progressive patients (13.1%) were identified. Results from the sensitive analysis showed that the median incubation period from HIV infection to AIDS was between 8.5 and 8.9 years, with incidence as 11.7-12.0 cases/100 person-years and the median survival time for HIV progression to death was from 8.8 to 10.7 years, with the death rate as 6.9-8.3 cases/100 person-years. The median survival time for AIDS patient was from 1.2 to 2.0 years, with death rate as 34.9-51.5 cases/100 person-years. Conclusion According to sensitive analysis, the incubation period for HIV progression to AIDS, the median survival time for HIV progression to death and the median survival time for AIDS patient to death were 8.8 years, 1.2 years and 9.8 years,respectively.
RESUMO
<p><b>OBJECTIVE</b>To study incidence and death among previous paid blood-donated AIDS sufferers.</p><p><b>METHODS</b>A retrospective cohort study was adopted to study incidence and death of 373 previous paid blood-donated HIV sufferers and its effect factors.</p><p><b>RESULTS</b>Previous paid blood-donated HIV infection was serious and the infection rate in blood-donated crowd was 35.87% (373/1040); the mean incubation period of AIDS was 8.87 years (95% CI: 8.76 - 8.99, Kaplan-Meier method); the cumulative incidence of AIDS (10 years) was 92.23% (344/373), and the incidence of total sufferers was 11.64/100 person-year; the cumulative probability of survival of one-year, three-year, five-year AIDS sufferers was separately 94.48% (325/344), 85.76% (295/344) and 83.14% (286/344), median survival time was over 5 years; the anti-virotic treatment days (960.29 +/- 486.38), infection age (33.39 +/- 9.08) disease age (41.98 +/- 8.88) had significant effects on AIDS sufferers' survival time/survival rate (chi(2) = 61.355, P = 0.000; chi(2) = 6.555, P = 0.010; chi(2) = 3.969, P = 0.046).</p><p><b>CONCLUSION</b>The survival time of previous paid blood-donated HIV cases was longer, and their survival rate was higher, remarkably higher than the UNAIDS' research findings.</p>