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Objective To investigate the value of the expressions of estrogen receptor(ER)and progesterone receptor(PR)in the cast-off cells from the fluid of latex ductal lavage in the diagnosis and treatment of breast diseases.Methods A total of 58 female out-patients were examined by fiberoptic ductoscopy(FDS).All patients were divided into 6 groups by the complaints,physical examination,ultrasound and FDS:normal group(10 persons without symptoms and abnormalities in any examination),galactostasis group(n=19),latex fill up group(n=11),intraductal papilloma group(n=2),mammary ductal ectasia group(n=7)and contralateral examination after mastectomy for breast cancer group(n=9).A total of 168 ducts were successfully examined by FDS,and the expressions of ER and PR in the cast-off cells were detected among all of the samples.Results The positive rates of ER and PR expression in the cast-off cells from the fluid of latex ductal lavage in benign breast disease groups were much higher than those in normal group(P
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Objective To discuss the clinical value of f iberoptic ductoscopy in the diagnosis and treatment of breast diseases. Methods A total of 3 000 patients with mastalgia, breast mass or ni pple discharge received examinations by fiberoptic ductoscopy. Cytological exami nations were carried out in part of the patients after ductoscopy. Resu lts Of the 3 000 cases, there were 608 cases of intraductal space-occup ying lesions, 1 709 cases of obstructive galactophoritis, 350 cases of galactost asia, 24 cases of acute galactophoritis, 282 cases of simple mammarv duct ectasi a, and 27 cases of normal mammary ducts. Of 1 167 patients with nipple discharge , intraductal space-occupying lesions were clarified by ductoscopy in 585 cases (50%). Surgery was performed in 643 cases while intraductal interventional thera py was adopted in 2 365 cases. Conclusions Fiberoptic ductosco py may be used for the diagnosis and treatment of various breast diseases, not c onfined to nipple discharge.
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Objective To evaluate the application of u lt rasound guided Mammotome minimally invasive biopsy system in the diagnosis and t reatment of breast mass. Methods B-ultrasound guided stereotac tic core breast biopsy using the Mammotome system was conducted in 221 breast ma sses of 132 patients. Unilateral solitary masses were found in 79 patients and u nilateral or bilateral multiple masses, in 53 patients. The mass was 0.5~5.2 cm (mean, 1.4 cm) in diameter. Of the 221 masses, 149 were clinically palpable. Results All the lesions were removed by using the Mammotome syste m. The stereotactic excisional biopsy was performed for a mean of 24 times, last ing a mean of 36 min (range, 10~40 min). No failed procedure occurred. All the m asses were pathologically confirmed as benign lesions in 129 patients and invasi ve ductal carcinomas in 3 patients (a modified radical mastectomy was then perfo rmed). Postoperatively, the incision scar was barely visible and no complication s happened except for mild subcutaneous hemorrhage in 10 patients. Conc lusions Use of B-ultrasound guided stereotactic core breast biopsy usin g the Mammotome system for the removal of benign breast lesions is convenient, e ffective, and minimally invasive.