RESUMO
Objective: To explore clinical effect of treating acute coronary syndrome [ACS] of renal transplant recipients with percutaneous coronary intervention and its safety
Methods: Forty two renal transplant recipients who were diagnosed with acute coronary syndrome and received percutaneous coronary intervention [PCI] in our hospital were selected. Serum creatinine [Cr] and glomerular filtration rate [GFR] were compared before surgery, 48 [tilde] 72 hour after surgery and one year after surgery. All patients were followed up
Results: All patients successfully completed PCI. Contrast-induced nephropathy was not found after surgery. Cr and GFR 48 [tilde] 72 hour after surgery and one year after surgery had no significant differences with that before surgery [P>0.05]. The follow up lasted for [61.2 +/- 32.2] months averagely. Of 42 cases, 4 cases died, 6 cases were found with nonfatal myocardial infarction, 4 cases were observed with repeat revascularization and 12 cases had accumulative major adverse cardiovascular events [MACE]
Conclusion: PCI is proved to be effective in treating renal transplant recipients; no severe complications are found and renal function recovers well after treatment
RESUMO
Objective:To discuss the influence and curative effect of bifidobacterium tetravaccine tablets on serum substance P ( SP) and neuropeptide Y ( NPY) levels in the patients with irritable bowel syndrome ( IBS) . Methods: Totally 84 cases of patients with IBS were selected and divided into the observation group and the control group at random. The patients in the two groups were both given the medical treatment, such as diet adjustment, malntenance of water and electrolyte acid-base balance, administration of gastro-intestinal antispasmodic and antidiarrheal agents. The patients in the observation group were additionally given 0. 15g bifidobacterium tetravaccine tablets per time, three times a day for 8 weeks. The changes of serum SP and NPY levels in the two groups before and after the treatment were observed, and the clinical curative effect and adverse drug reaction ( ADR) were compared. Results:After the 8-week medical treatment, the serum SP level in the two groups was obviously declined than that before the treatment, while the NPY lev-el was obviously ralsed than that before the treatment (P0. 05). Conclusion:Bifidobacterium tetravaccine tablets show reli-able curative effect on IBS with high security, and the curative effect has close relationship with inhibiting the release of SP, enhancing the release of NPY, adjusting the excitement of braln gut axis and inhibiting the imbalance of braln gut petide in the patients with IBS.