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@#Objective To investigate the occurrence and characteristics of dysphagia and aspiration in the elderly in nursing home in Weifang, Shandong, China.Methods From January to June, 2021, 837 elderly people from 10 nursing homes in Weifang were randomly selected and investigated with general situation questionnaire, Fried Frailty Phenotype, Ohkuma questionnaire and Volume-Viscosity Swallowing Test.Results The prevalence of dysphagia and aspiration was 44.2% and 12.3% respectively. There were significant differences in the prevalence of dysphagia among ages and health condition (χ2 > 8.437, P<0.05). The prevalence of dysphagia and aspiration was higher in men than in women (χ2 > 4.060, P < 0.05). The incidence of oral dysphagia was higher in men than in women, and the incidence of esophageal dysphagia was lower (χ2 > 20.830, P<0.001). Oral dysphagia was predominant in the elderly with stroke, Alzheimer's disease, and Parkinson's disease (χ2=27.579, P<0.001), and esophageal dysphagia and airway protection dysfunction were predominant in the elderly with chronic respiratory disease (χ2 > 20.241, P<0.01).Conclusion The dysphagia and aspiration are prevalent in the elderly in nursing homes, and varies with different genders and basic diseases.
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To observe possibility whether exfoliative cervical cell takes the place of cervical tissues for detection of human papilloma virus 16 and 18 types (HPV16 and HPV18). Polymerase chain reaction-restrictive fragment length polymorphism was used for analysis cervical tissues, single and double oxfoliative cervical cell samples of 127 cases of woman patients. Positive rates of HPV16 E6 Gene in single and double oxfoliative cervical cell are 34.64% and 40.73%, for HPV18 E6 gene 17.32% and 22.04%. In cervical tissues, 41.73% of HPV16 and 22.83% HPV18 special E6 genes was detected. There is no difference between cervical tissues and double oxfoliative cell samples. It is proved that double oxfoliative cervical cell sample can be used for detection of infection of HPV 16 and HPV 18 instead of cervical tissues.