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Journal of Zhejiang University. Science. B ; (12): 488-495, 2019.
Artigo em Inglês | WPRIM | ID: wpr-776714

RESUMO

Exosomes and long non-coding RNAs (lncRNAs) are emerging as important elements contributing to a more comprehensive understanding of cancer development and progression. The discovery of lncRNAs in exosomes further indicates their bona fide biological functional roles in cancer development and drug resistance. In this review, we describe the biogenesis of exosomes and summarize the function of exosomal lncRNAs in the field of cancer research. These findings strikingly advance current knowledge of exosomal lncRNAs and suggest that they may be promising diagnostic biomarkers and therapeutic targets for cancer.


Assuntos
Humanos , Exossomos , Fisiologia , Neoplasias , Diagnóstico , Genética , Terapêutica , RNA Longo não Codificante , Fisiologia
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