Study on response of resting-state functional magnetic resonance imaging induced by abdominal acupuncture with invigorating the kidney and nourishing marrow method / 中国针灸

<p><b>OBJECTIVE</b>To approach the central nervous mechanism of abdominal acupuncture by using resting-state functional magnetic resonance imaging (fMRI).</p><p><b>METHODS</b>Twelve old healthy volunteers were treated by standardized abdominal acupuncture with invigorating the kidney and nourishing marrow method and Zhongwan (CV 12), Xiawan (CV 10), Qihai (CV 6), Guanyuan (CV 4), Qixue (KI 13), Shangqu (KI 17) and Huaroumen (ST 24) were selected. They were examined by using resting-state fMRI before and after treatment of abdominal acupuncture and the brain functional connectivities were analyzed based on bilateral hippocampus chosen as seed points.</p><p><b>RESULTS</b>(1) Before acupuncture, functional connectivities were found in the bilateral middle frontal gyrus, bilateral superior temporal gyrus, bilateral middle temporal gyrus, bilateral thalamus, bilateral subiculum hippocampi, bilateral insula, the cupula and declivis of right cerebellum, left superior frontal gyrus, left head of caudate nucleus, left posterior cingulate gyrus and left inferior parietal lobule (all P < 0.05). (2) After acupuncture, functional connectivities were found in the bilateral superior frontal gyrus, bilateral superior temporal gyrus, bilateral middle temporal gyrus, bilateral thalamus, bilateral insula, bilateral subiculum hippocampi, bilateral inferior parietal lobule, bilateral postcentral gyrus, bilateral cingulate gyrus, right head of caudate nucleus, right middle occipital gyrus and right posterior cingulate gyrus (all P < 0.05). (3) After acupuncture, there were intensity functional connectivities greater than before acupuncture in the bilateral superior frontal gyrus, bilateral middle frontal gyrus, bilateral superior temporal gyrus, bilateral superior parietal lobule, right inferior frontal gyrus, right anterior cingulate gyrus, right fusiform gyrus, right precuneus and right postcentral gyrus, while the intensity of functional connectivities of left middle temporal gyrus, right lingual gyrus, left cuneus/precuneus and left inferior parietal lobule were attenuated.</p><p><b>CONCLUSION</b>Abdominal acupuncture with invigorating the kidney and nourishing marrow method can improve the allomeric function of the brain cognition network of central nervous system.</p>

Acupuncture at the acupoints of different meridians at the same anatomy level: a study with functional magnetic resonance imaging / 南方医科大学学报

<p><b>OBJECTIVE</b>To investigate the response of the specific brain functional areas of normal human to acupuncture at the acupoints of different Meridians at the same anatomy level.</p><p><b>METHODS</b>Twelve healthy young volunteers were enrolled in this research and functional magnetic resonance imaging (fMRI) scans were taken randomly in a block design. During the stimulation phase, an acupuncture needle inserted in right Shenmen (HT7) or Yanglao (SI6) was twirled at an angle of 180 degrees and a frequency of about 1.5 Hz. The collected images were analyzed using SPM2 for exploring the inter-group differences in blood oxygen level dependent (BOLD) responses. RESULTS Increases in BOLD signal (group analysis, corrected, 0.05, K>or=10) were found mainly in the right ostcentral gyrus of the frontal lobe (BA2, BA1, BA43) and left inferior frontal gyrus (BA47) by acupuncture at HT7, and chiefly in the left inferior parietal lobule (BA 40) and right inferior frontal gyrus (BA 45, BA 46) by acupuncture at SI6.</p><p><b>CONCLUSION</b>Acupuncture of HT7 and SI6 elicits different BOLD responses in some related cerebral regions correlative with cognition.</p>