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[Objective] To explore the relationship between laterality of auditory brainstem response and speech comprehension in children with autism spectrum disorders preliminarily.[Method] Review hearing diagnosis data in clinical audiology center from September 2013 to August 2015.We compare auditory brainstem responses in children with autism spectrum disorders (ASD group) and with other disorders (control group),and we further divide children with autism spectrum disorders into two groups (high ability group and low ability group) in terms of their speech comprehension and compare their auditory brainstem responses.[Result] The latencies of waves Ⅲ and Ⅴ,and interpeak latencies Ⅰ to Ⅲ and Ⅰ to Ⅴ of the ASD were significantly prolonged than the control group.And the laterality of waves Ⅲ and Ⅴ,and interpeak latencies Ⅰ to Ⅲ and Ⅰ to Ⅴ present in the ASD group,but not in the control group.Meanwhile,the laterality of waves Ⅲ and Ⅴ,and interpeak latencies Ⅰ to Ⅲ and Ⅰ to Ⅴ present in the high ability group,but not in the low ability group.[Conclusion] Laterality was not a common phenomenon in auditory brainstem response,and it may be associated with the development of speech comprehension in children with autism spectrum disorders.
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Objective To analyze the clinical characteristics of auditory neuropathy under pure tone audiometry and acoustic immitance examination.Methods Seventeen patients (32 ears) diagnosed as having auditory neuropathy were examined for audiology features by pure tone audiometry and acoustic immitance.Results Bilateral and symmetrical hearing loss was found in 15 patients and low-frequency sensorineural hearing loss was noted in 26 ears.Seventeen ears with a course of disease less than 5 years presented light or moderate dysaudia,and those with more than 5 years presented grave loss of aural comprehension.16 patients (31 ears) in the acoustic immitance examination showed type A tympanogram,and absence of stapedius muscle reflex was found in 15 patients (30 ears).The threshold of acoustic stapedius reflex increased in 2 patients (2 ears).Conclusion Auditory neuropathy primarily presents bilateral and symmetrical hearing loss,low-frequency hearing loss at the initial stage and total-frequency hearing loss finally,absence of stapedius muscle reflex and type A tympanogram,and absence of loudness recruitment phenomenon.
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<p><b>OBJECTIVE</b>To investigate the hearing change when chronic tinnitus acute aggravated and the affect of prognosis due to hearing change.</p><p><b>METHODS</b>The pure tone threshold and acoustic immittance were used for every case in the acute aggravation of chronic tinnitus (AACT) group, and for some of AACT group members the auditory brainstem response (ABR), distort-product otoacoustic emission (DPOAE), electrocochleogram (EcochG), glycerin test and MRI were used at the same time for further diagnosis. For the chronic tinnitus, the patients accepted the intervention of tinnitus retraining therapy (TRT) both for the AACT group and the control group. As for the recent hearing loss appeared in the AACT group members, the patients were treated the cases as the sudden deafness, and then the hearing characteristic of the AACT group was analyzed and the effect of the chronic tinnitus both for the AACT group and control group after the TRT for 3, 6, 9 and 12 months was evaluated.</p><p><b>RESULTS</b>Three kinds of hearing changes appeared when chronic tinnitus acute aggravated. Based on the dated high frequencies hearing loss ranged 4-8 kHz, recent hearing loss appeared in 1-2 middle frequencies near the impaired high frequencies; Based on the dated single middle frequency hearing loss, another middle frequency hearing impaired near the dated hearing loss frequency, the sawtooth-like audiogram changed to groove-like audiogram; Hearing fluctuation in low frequency area, hearing threshold increased 10-30 dB in 125-1000 Hz but kept unchanged in the high frequency area. The recent local frequency hearing loss healed after the vasodilator and neurotrophic drugs therapy, but the dated hearing loss can't rehabilitate. Along with the rehabilitation of recent local hearing loss, 25 of 32 cases chronic tinnitus victims get to habituation; this finding showed that the experience of tinnitus aggravation and relief accelerated the habituation. Until the 12 months after the TRT, the curative effect difference between AACT group and control group showed statistical significance.</p><p><b>CONCLUSIONS</b>When the chronic tinnitus acute aggravated, 3 kinds of local area hearing impaired. Timely diagnosis and effective treatment had brought not only hearing rehabilitation but also promotion to habituation of chronic tinnitus.</p>