RESUMO
Objective:To analyse the skin clinical characteristics of adverse reactions to cosmetic products.Methods:A total of 132 patients suffered with the skin adverse reactions of cosmetics were collected in the Department of Dermatology in the First Affiliated Hospital of Xinxiang Medical University from January 2021 to December 2021. There were 5 males and 127 females, aged 2-66 (34.0±13.1) years. and the personal information, medical records, clinical characteristics and the cosmetic information as well as laboratory results were collected.Results:The major types of adverse reactions to cosmetic products were contact dermatitis (86.4%). Head was the most commonly affected site, The most common symptoms were pruritus and burning sensation (83.9%), and sores, dryness, tightness of the skin, and the common skin lesions included erythema and papula (92.9%). Suspected cosmetics were mostly skin care products (45 cases) and freckle removing products (30 cases). Only 7 patients accepted patch tests, 1 case had negative results and others were all tested positive.Conclusions:Adverse drug reactions affect young and middle-aged women mostly. Contact dermatitis is the most common adeverse reaction to cosmetic products and the patch test is still the most effective method in helping diagnosing contact dermatitis to cosmetic products.
RESUMO
OBJECTIVE: To observe the clinical efficacy of Jinhua xiaocuo pill and 0.05% taiarotene cream in the treatment of acne vulgaris. METHODS: 64 patients with acne vulgaris were randomly divided into experimental group and control group according to visiting order, the cases of 2 groups were 32. Experimental group were treated with 4 g Jinhua xiaocuo pill p.o. and 0.05% taiarotene cream for external use once every evening. Control group were treated with chloramphenicol/metronidazole liniments three times a day, the treatment course of 2 groups were 6 weeks. Efficacy before and after treatment were evaluated and analyzed with SPSS 13.0 software. RESULTS: The effective rate was 93.8% for experimental group and 65.6% for control group. Significant different was noted between two groups(?2=7.169,P
RESUMO
OBJECTIVE: To study the clinical efficacy of Nalmefene in the treatment of chronic type Ⅱrespiratory failure. METHODS: A total of 40 patients with chronic type Ⅱ respiratory failure were randomly divided into treatment group and the control group: the treatment group received Nalmefene (1.0 mg) plus 5% GS (250 mL) q.d by iv gtt. in addition to the routine treatment, and the control group received 1.875 g Nikethamide plus 5% GS (250 mL) q.d by iv gtt. After 5-day treatment, the clinical symptom, physical signs, adverse drug reactions, lung function testing and blood gas analysis in two groups were evaluated. RESULTS: The overall response rate was 95.0% in the treatment group vs. 60.0% in the control group(P