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Tumor cell proliferation activity is related with tumor biological behavior. PCNA (proliferating cell unclear antigen, PCNA) is a kind of histone nucleoprotein, is associated with cell proliferation and DNA synthesis,can reflect the degree of cell proliferation and cycle period, it is as a cell proliferation activity indicator, has been widely used in a variety of tumor research,the expression of PCNA in common head and neck tumor can be used as the biological behaviour and prognosis judgement.
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0.05).Conclusion Ultrasound-guided injection of APG is one of the easy,safe,and effective methods for femoral artery pseudoaneurysm.
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Objective To investigate the effect of nerve growth factor (NGF) on recuperate of optic nerve after contusion by clamping in adult rabbits. Methods Sixteen adult rabbits were randomly divided into NGF and the control group with 8 rabbits in each group. After the optic nerve of the right eyes was clamped,tissue engineering nerve containing (0.06 ml) NGF(concentration: 5?10~(-4) g/L, NGF group) and 0.06 ml of PBS (control group) was immediately transplanted into the injured eyes respectively, and 0.02 ml NGF(concentration: 5?10~(-4) g/L, NGF group)and 0.02 ml of PBS (control group) were injected into the vitreous of right eyes respectively. Flash visual evoked potential (FVEP) test was performed on the eyes 1 day, 2 weeks and 8 weeks after the injury. The number of retinal ganglion cells (RGCs) and changes of optic nerves were observed by light microscopy and electron microscopy at the 8th week after contusion,and a computer-image-analysis system was used to count the optic nerve axons. Results The ratio of amplitude of FVEP of the injured and healthy eyes was 0.765?0.150 in NGF group and 0.494?0.108 in the control at the 2th week after injury with a significant difference between the two groups (P