Erdheim-Chester disease with multiple serous cavity effusion: a case report / 中国综合临床

Erdheim-Chester disease is a rare non-Langerhans histiocytic disease that can involve multiple systems, such as bone and joint, nerve, skin, large blood vessels and endocrine.The most common clinical manifestation is slight bone pain around the lower limb joints. The data reported a patient with multiple serous cavity effusion as the first manifestation and lack of symptoms of bone pain. PET-CT examination showed that the bone and large blood vessels were involved, and finally confirmed as Erdheim-Chester disease by bone biopsy pathology. The patient presented atypical manifestations of rare diseases, and the analysis of clinical data of the case will help improve the recognition of the disease by clinicians.