The research of serotoninergic pathway function of dorsal raphe nucleus / 医学研究生学报

The 5-hydroxytryptamine(5-HT) neurons in the dorsal raphe nucleus(DRN) project to a wide area of the brain and are associated with many physiological processes and the occurrence of mental disorders, such as sleep-arousal, anxiety, reward, depression, neuroplasticity, et al. . However, the mechanisms of there functions on 5-HT neurons are unclear. This article start from neural network and review the relative signaling pathway of 5-hydroxytryptamine neurons in anxiety, reward and drug addiction.