1.
Chinese Journal of Marine Drugs
;
(6)1994.
Artigo
em Chinês
| WPRIM
| ID: wpr-581693
RESUMO
Six new sesquiterpenoid compounds of nerve-activity were synthesized from a gorgonian neurotoxin -subergorgic acid (1). Toxicological studies and structural correlation with toxicity reveal that subergorgic acid may act on cholinesterase and make a reversible inhibition of its activity of hydrolysis.
2.
Chinese Journal of Marine Drugs
;
(6)1994.
Artigo
em Chinês
| WPRIM
| ID: wpr-581894
RESUMO
Subergorgic acid is one of marine neurotoxins. It has a unique chemical structure. This article reviews its isolation and structural determination, total synthesis,derivatives preparation,biologic activities and potential applications.