RESUMO
Objective To explore the optimal conditions of the vacuum-belt drying process of Rhizoma Chuanxiong extract.Methods Influencing factors of the vacuum belt drying process of Rhizoma Chuanxiong extract were studied by using orthogonal test.The water content and ferulic acid content of dried product were used as the quality indicators.Results The optimal parameters of the vacuum-belt drying process were as follows:the heated region temperature being 95 ℃,the feeding speed at 10 Hz/s,and the belt speed at10 Hz/s.Conclusion The vacuum-belt drying techniquefor drying the extract brings high drying rate and high quality product.This study can provide a reasonable basis for industrial production in line with the GMP requirements.
RESUMO
Objective To observe the microfiltration of different types of ceramic membrane for aqueous extract of Rhizoma Chuanxiong,and to select the optimal type of ceramic membranes. Methods The aqueous extract of Rhizoma Chuanxiong was microfiltered by inorganic ceramic membranes in the pore diameter of 50 nm,200 nm,and 500 nm,respectively. The characters,total solids,and active ingredients of the aqueous extract were analyzed and compared before and after microfiltration. Results The aqueous extract turned into clarified liquid from turbid liquid after microfiltration with the three types of the inorganic ceramic membrane. The removal rate for total solids was 25.7 %,26.5 %and 25.9 %,and the loss rate for ferulic acid was 12 %,6 %and 4 %,respectively for the inorganic ceramic membranes in the pore diameter of 50 nm,200 nm,and 500 nm. Conclusion Both the yield of dry solid material and ferulic acid are stable during the three middle-scale tests,indicating that he aperture ceramic membrane in the pore diameter of 200 nm is a optimal selection for the purification and refining of aqueous extract of Rhizoma Chuanxiong.