Laparoscopic side-to-side jejunoileal anastomosis for the treatment of non-obese type 2 diabetes mellitus / 中华普通外科杂志

Objective:To analyze the feasibility, safety and clinical efficacy of laparoscopic side-to-side jejunoileal anastomosis in the treatment of non-obese type 2 diabetes patients (BMI≤32.5 kg/m 2). Methods:The clinical data of 135 patients who underwent laparoscopic side-to-side jejunoileal anastomosis at our hospital from Jan 2018 to Oct 2018 were retrospectively analyzed. They were followed up for 12 months until the end of Oct 2019. SPSS software was used to compare patients′ fasting blood glucose, glycosylated hemoglobin, c-peptide, insulin, body weight, BMI with the values after 12 months of the surgery, and then evaluate factors affecting the prognosis.Results:135 patients successfully completed laparoscopic side-to-side jejunoileal anastomosis without conversion to open surgery. After 12 months of the operation, the patients′ fasting blood glucose was (5.80±0.18)mmol/L, glycosylated hemoglobin was 5.9%±0.4%, fasting c-peptide was(1.32±0.21) nmol/L, and fasting insulin was (42±54) mU/L ( t=10.654, 12.657, 11.214, 10.698, all P<0.05). The body weight was (72.4±9.9)kg, BMI was( 25.6±2.8)kg/m 2, and the difference was not statistically significant ( t=7.658, 6.958, P>0.05). In patients with preoperative glycosylated hemoglobin controlled below 8% and the duration of T2DM less than 10 years, the chances being cured was better than that of those with glycosylated hemoglobin>8% and the medical history >10 years. Conclusion:Laparoscopic side-to-side jejunoileal anastomosis in the treatment of non-obese type 2 diabetes is effective, safe and reliable.

Relationship between family behavior factors and overweight/obesity in primary and junior school students / 中国学校卫生

Objective@#To analyze the relationship between family behaviors and overweight/obesity in primary and junior school students aged 6-14 years in Xuzhou, and to provide a reference for a targeted measure to prevent and control overweight and obesity.@*Methods@#Using multistage stratified cluster random sampling, a total of 6 220 students aged 6-14 years old from 10 primary schools and 10 junior schools were investigated by a self-designed questionnaire. Chi-square and multivariate Logistic regression models were used to explore the relationship between family behaviors and overweight/obesity in primary and junior school students.@*Results@#The rate of overweight/obesity in primary and junior boys was higher than that in primary and junior girls. The rate of overweight/obesity in urban students was higher than that of rural students(P<0.05). The Chi-square analysis showed that overweight of parents, irregular breakfast, eating fast food, eating sweets, drinking sweetened beverage, long screen time and short sleep duration were risk family behavior factors of overweight/obesity in primary and junior boy students(P<0.05). The risk family behavior factors of overweight/obesity in primary and junior girl students were overweight of parents, irregular breakfast, eating fast food and eating sweets(P<0.05). The risk family behavior factors of overweight/obesity, such as drinking sweetened beverage and short sleep duration, were also related to primary girls(P<0.05), and long screen time was related to junior girls(P<0.05). The multivariate Logistic regression showed that such family behavior factors as irregular breakfast(OR-boy=1.58, OR-girl=1.74), eating fast food(OR-boy=1.37, OR-girl=1.11), eating sweets(OR-boy=1.85, OR-girl=1.52), drinking sweetened beverage(OR-boy=1.64, OR-girl=1.33) and short sleep duration(OR-boy=1.56, OR-girl=1.69) were positively correlated with the prevalence of overweight/obesity in primary students. Long screen time was also correlated to overweight/obesity primary boy students(OR=1.18). Family behavior factors for child overweight and obesity induded overweight of parents(OR-boy=1.29, OR-girl=1.23) and eating sweets(OR-boy=1.44, OR-girl=1.51). Irregular breakfast(OR=1.51), eating fast food(OR=1.22), drinking sweetened beverage (OR=1.75) and long visual screen time (OR=1.15) were also positively correlated with the prevalence of overweight/obesity in junior boy students.@*Conclusion@#Family behavior factors were positively correlated with the prevalence of overweight/obesity in primary and junior students. The influence of family behavior factors were different between primary and junior students. Behavioral interventions based on family should be adopted to prevent and control the overweight/obesity of children.

Clinical application of short 5 Fr pancreatic duct stent in difficult biliary cannulation of ERCP / 中国内镜杂志

Objective To investigate the clinical applicative of short 5 Fr pancreatic duct (PD) stents in difficult biliary cannulation of ERCP. Methods 131 patients who underwent difficult biliary cannulation during routine ERCP were randomized to receive prophylactic short 5 Fr PD stents (stent group, 66 patients) and not (control group, 65 patients) from January 2012 to October 2015. The success rate of biliary cannulation for the first ERCP, scores of abdominal pain, the incidence of post-ERCP pancreatitis (PEP) and hyperamylasemia and severe post-ERCP pancreatitis were analyzed. Results The success rate of biliary cannulation for the first ERCP was significantly higher with the stent group than the control group. The scores of abdominal pain of the stent group was significantly lower than the control group. The postoperative serum amylase value at 3 h and 24 h were obviously lower in PD stents group than those in control group. The incidence of hyperamylasemia, post-ERCP pancreatitis, severe post-ERCP pancreatitis were also significantly lower with PD stents group than the control group. 3 cm long 5 Fr PD stents has high success rate of placement, high spontaneous migration rate, low complications, decreases the need for endoscopic removal. Conclusion In difficult biliary cannulation during ERCP, placement of short 5 Fr PD stent is safe and effective, enhance the success rate of biliary cannulation, relieve the abdominal pain, reduces the rate of post-ERCP pancreatitis efficiently.

Effect of Different Anesthetics on Emergence Agitation after General Anesthesia / 昆明医科大学学报

Objective To explore the influence of different anesthetics on emergence agitation (EA) after general anesthesia. Methods 134 EA patients after general anesthesia were randomly divided into three groups. Group A (n=42), Group B (n=45) and Group C (n=47) was given intravenously parecoxib 40 mg, butorphanol 20μg/kg and tramadol 1 mg/kg, respectively. The improvement of agitation, VAS score and Ramsay score were compared and analyzed among the groups. Results After treatment, the degree of EA in Group A, Group B was significantly lower than that in Group C ( <0.05) . VAS score in all the cases was reduced, and Ramsay score was increased compared with that before treatment ( <0.05) . VAS score in Group C was significantly higher than that in Group A, Group B (<0.05) . Ramsay score in Group B was significantly higher than that in Group A, Group C (<0.05) . After treatment, awaking time and postanesthesia care unit (PACU) stay in Group B was significantly higher than that in Group A, Group C (<0.05) .Conclusions Parecoxib is safe and effective for EA after general anesthesia, it can effectively improve the degree of EA, increase postoperative sedative effect, and shorten PACU stay.

The Correlation Between the Elevation of IL-2 and IL-10 Levels Under Mild Hypothermia and Early Postoperative Cognitive Dysfunction in Elderly / 昆明医科大学学报

Objective To compare the effects of mild hypothermia or normothermia on inflammatory cytokines (IL-2 and IL-10) in elderly patients undergoing surgery for rectal cancer, and determine whether the elevation of IL-2 and IL-10 levels and early postoperative cognitive dysfunction has the relevant. Methods Forty ASA classification Ⅰ or Ⅱ patients aged 65-83 yr undergoing surgery for rectal cancer were randomly divided into 2 groups (n=20 each):normal body temperature group (GroupⅠ) and mild hypothermia group (GroupⅡ) . The venous blood samples were taken at 3 points which were at 1 h before anesthesia (T1), the end of operation (T2) and the 24h after operation (T3) to measure the levels of plasma IL-2 and IL-10. The cognitive function test (MMSE) were performed at one day before operation (N1), one day after operation (N2) and 3th days after operation (N3) . Results The level of plasma IL-2 was significantly lower in the GroupⅡthan that in the GroupⅠat T2 and T3 ( < 0.01), and those was significantly lower at T3 than that at T2 ( <0.01) . The level of plasma IL-10 was significantly higher in the GroupⅡat T3 than that at T1 and T2 ( <0.01) . To compare with N1, the score of both groups were decreased at N2 ( <0.05), and it was lower in GroupⅡthan that in GroupⅠ( <0.05), with a significant difference. The score of both groups were increased significantly at N3 (<0.05), and there was significant difference with N2 ( <0.05);Positive correlation was found between IL-2 at T2 and T3 and the score of MMSE in the GroupⅡat N2 ( =0.459, <0.01) ( =0.550, <0.01) . Conclusion Positive correlations were found between the elevation of IL-2 levels under mild hypothermia and the decline of postoperative early cognitive function in elderly undergoing rectal cancer surgery.

Effects of exogenous nitric oxide on hippocampus gaseous transmitters in rats with global cerebral ischemic-reperfusion injury / 临床麻醉学杂志

Objective To investigate the effects of exogenous nitric oxide (NO) on gaseous transmitter molecule of the hippocampus in rats with global cerebral ischemic-reperfusion(I-R) injury.Methods Twenty-four Wistar male rates were randomly divided into 4 groups of sham operation (group S),I-R control(group I-R),I-R plus sodium nitroproside(SNP) 2 mg/kg(LSNP) or plus SNP 4 mg/kg(group HSNP) with 6 rats each.Global cerebral I-R model was established by 4-vessel occlusion.SNP was injected at 30 min before clamping the bilateral carotid arteries in groups of LSNP and HSNP.The carotid arteries were clasped for 20 min.The rats were killed after cerebral reperfusion for 6 h.The concentrations of hydrogen sulfide(H_2S),NO and CO,the activity of cystathionine beta synthase(CBS),HO and inducible nitric oxide synthase(iNOS),as well as the expression levels of CBS mRNA,iNOS mRNA and hemeoxygenase-1 (HO-1) mRNA in the hippocampus were measured.Results Compared to group S,the concentrations of H_2S,NO and CO,the activities of CBS,HO and iNOS and the expressions of CBS mRNA,iNOS mRNA and HO-1 mRNA in group I-R were increased(P<0.05 or P<0.01) ,which were all higher in groups of LSNP and HSNP than those in group I-R(P<0.05 or P<0.01).Conclusion Exogenous NO can induce the expressions of CBS mRNA and HO-1 mRNA,activate CBS and HO in rats with global cerebral I-R injury,indicating that NO has a modulation effect on the CBS/ H_2S and iNOS/NO systemes.

Study on the immune modulations of obstructive sleep apnea syndrome / 中国医师进修杂志

Objective To investigate the effect of the activity of CR1, the expression of CD_ 58 , the level of soluble interleukin-2R (SIL-2R) and interleukin-6(IL-6) level in serum on obstructive sleep apnea syndrome (OSAS). Methods Select 20 OSAS cases in hospital and 15 healthy controls of the same age. Use flow cytometry and enzyme-linked immunosorbent assay(ELISA) to detect the activity of CR1, the expression of CD_ 58 and the level of SIL-2R, IL-6 in serum. Results (1)The erythrocytes cancer cell rosette(ECR1CaRR)of the OSAS group was lower than that of control group(P0.05). There were significant positive dependability between the level of SIL-2R,IL-6 in serum and SIT90(P0.05). Conclusions There are relations between the level of SIL-2R,IL-6 in serum and the condition of OSAS cases, which can be used to evaluate and define in clinical work,there is a accommodative role between erythrocyte immune function and some cytokines.

The Relationship between Parental Rearing and Adolescent Personality Traits / 中国临床心理学杂志

Objective: To examine the relationship between parental rearing and adolescent personality traits. Methods: A sample of 637 adolescents was tested by CAPI and EMBU. Results: Neuroticism of girls is higher than that of boys, but interpersonal harmony, face and defensiveness of boys is higher than those of girls. Extraversion, openness and agreeableness of only child is higher than those of other adolescents. Most correlations between parental rearing and Adolescent personality traits are significant. Parental warmth and understanding have positive effect on adolescent extraversion, agreeableness and conscientiousness, and father punishment and mother refusal have negative effect on adolescent agreeableness and interpersonal relationship. Conclusion: Adolescent personality is greatly affected by parental rearing.

Parents’Patterns of Rearing and Educating and Their Relationship to Self-concept of Adolescents / 中国临床心理学杂志

Objective: To examine the parents’rearing and educating patterns and their relationship to the characteris- tics of self- concept of adolescents. Methods: A sample of 313 adolescents was tested by the Self- concept Scale and the revised EMBU. Results: Physical self and character self of boys are higher than those of girls. Family self of adolescents whose father has high education level is higher than that of adolescents whose father has low education level(P

Impacts of Sex,Gender Role on Undergraduates' Gender Belief / 中国临床心理学杂志

Objective:To examine the difference of undergraduates' gender belief in sex and gender role stereotype.Methods:A sample of 552 undergraduates was tested by BSRI and gender belief stereotype scale.Results:①Traditional gender belief of academic,occupation and family has difference on sex and gender role stereotype.②Men college students have higher traditional gender belief of academic,occupation and family than women college students.③College students of masculinity and undifferentiation have higher traditional gender belief of academic and occupation than college students of androgynous and femininity.College students of masculinity have higher traditional gender belief of family than college students of femininity,androgynous and undifferentiation.Conclusion:College students of men and masculinity have higher gender belief of academic,occupation and family.

Learning Style, Academic Self-concept and Academic Achievement / 中国临床心理学杂志

Objective: To explore the relationships among learning style, academic self-concept and academic achievement. Methods: In this research we employed scale of learning style and scale of academic self-concept to survey 609 middle-school students and primary students, and explored the relationships among learning style, academic self-concept and academic achievement. Results: ①Academic self-concept has correlation with academic achievement between 0.079 and 0.321; ②Different learning style students have differences in academic achievement; ③Different learning style students have significant differences in mathematical self-concept and academic self-concept total; ④Learning style and academic self-concept have significant predictive effect on academic achievement in total, mathematical achievement and Chinese achievement. Conclusion: Learning style and academic self-concept have effect on academic achievement and have significant predictive effect.

Probe into Personality Traits,Parental Rearing and Self-concept of Spring Bud Class / 中国临床心理学杂志

Objective:To examine the relationship of parental rearing,self-concept and personality traits of spring bud classes.Methods:A sample of 113 students,including spring buds' 30,non-spring buds' 30,and middle schools' 43,was tested by NEO-PI-R,CAPI,EMBU and Self-concept scale.Results:①Punishment of father,rejection and denial of mother and parental partiality of control group was higher than those of spring bud classes.②Family self-concept of spring bud classes was higher than that of non-spring bud classes.③Neuroticism of control group was higher than that of spring bud classes,but extraversion,human relationship orientation and flexibility of spring bud classes were higher than those of control group.④Partiality of father had positive correlation to extraversion and face of spring bud class students.Personality,moral and family self-concept had positive correlation to harmonious of spring bud class students.Conclusion:Personality and family self-concept of spring bud class students is greatly affected by parental rearing.