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Objective:To observe the clinical curative effect of compound glycyrrhizin tablets and tacrolimus ointmenta combined with photon therapy on hormone dependence facial dermatitis and the safety.Methods:80 cases were randomly divided into two groups: treatment group and control group, 40 each; compound glycyrrhizin tablets and tacrolimus ointmenta were administrated to all the cases in both groups while photon therapy was added to cases in treatment group; a comparative study was made to observe the clinical effect 4 weeks after treatment between the two groups.Results:Four weeks after treatment, the effective rate was 86.67% in treatment group and 63.33% in control group, the difference was of statistical significance ( χ2=4.36, P<0.05); the total scores of symptoms and signs decreased obviously in both groups while the difference between the groups was of statistical significance ( t=3.10, P<0.05); topical medication led to drug adverse reaction in 4 cases in treatment group and 3 cases in control group with the manifestation of tolerable aggravated facial erythema and twinge while the adverse reaction disappeared gradually with the drug application keeping on for about 1 week. Conclusions:Compound glycyrrhizin tablets and tacrolimus ointmenta combined with photon therapy is of definite curative effect on hormone dependence facial dermatitis with good safety.
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<p><b>PURPOSE</b>5.12 Wenchuan earthquake and 4.25 Nepal earthquake are of the similar magnitude, but the climate and geographic environment are totally different. Our team carried out medical rescue in both disasters, so we would like to compare the different traumatic conditions of the wounded in two earthquakes.</p><p><b>METHODS</b>The clinical data of the wounded respectively in 5.12 Wenchuan earthquake and 4.25 Nepal earthquake rescued by Chengdu Military General Hospital were retrospectively analyzed. Then a contrast study between the wounded was conducted in terms of age, sex, injury mechanisms, traumatic conditions, complications and prognosis.</p><p><b>RESULTS</b>Three days after 5.12 Wenchuan earthquake, 465 cases of the wounded were hospitalized in Chengdu Military General Hospital, including 245 males (52.7%) and 220 females (47.3%) with the average age of (47.6±22.7) years. Our team carried out humanitarian relief in Katmandu after 4.25 Nepal earthquake. Three days after this disaster, 71 cases were treated in our field hospital, including 37 males (52.1%) and 34 females (47.9%) with the mean age of (44.8±22.9) years. There was no obvious difference in sex and mean age between two groups, but the age distribution was a little different: there were more wounded people at the age over 60 years in 4.25 Nepal earthquake (p<0.01) while more wounded people at the age between 21 and 60 years in 5.12 Wenchuan earthquake (p<0.05). The main cause of injury in both disasters was bruise by heavy drops but 5.12 Wenchuan earthquake had a higher rate of bruise injury and crush injury (p<0.05) while 4.25 Nepal earthquake had a higher rate of falling injury (p<0.01). Limb fracture was the most common injury type in both disasters. However, compared with 5.12 Wenchuan earthquake, 4.25 Nepal earthquake has a much higher incidence of limb fractures (p<0.01), lung infection (p<0.01) and malnutrition (p<0.05), but a lower incidence of thoracic injury (p<0.05) and multiple injury (p<0.05). The other complications and death rate showed no significant differences.</p><p><b>CONCLUSION</b>Major earthquakes of the similar magnitude can cause different injury mechanisms, traumatic conditions and complications in the wounded under different climate and geographic environment.When an earthquake occurs in a poor traffic area of high altitude and large temperature difference, early medical rescue, injury control and wounded evacuation as well as sufficient warmth retention and food supply are of vital significance.</p>
Assuntos
Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Terremotos , Nepal , Prognóstico , Ferimentos e Lesões , EpidemiologiaRESUMO
A 54-year-old female presented with indurated nodules and plaques on the left chest and back for 32 years.Skin examination showed little finger- to soybean-sized,slightly whitish indurated nodules with little mobility arising on skin-colored indurated plaques following Blaschko's lines on the left chest and back.The lesional skin was sclerotic and atrophic,and the lesions were distributed unilaterally.Serum levels of calcium,phosphate,alkaline phosphatase and parathyroid hormone were normal.Histopathological examination revealed fibrous scar with flake-like calcification.The diagnosis was idiopathic calcinosis cutis following Blaschko's lines.