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Objective To summarize the efficacy and safety of diuretic mixture in the treatment of refractory heart failure.Methods One hundred and twenty patients with refractory heart failure were randomized into treatment group and control group.All the patients were treated with digitalis,diuretics,ACEI,nitrates,and strategies to control infection and correct water and electrolyte disorders.The treatment group was given additional diuretic mixture and was monitored for 7 days.Results In the treatment group and control group,the overall response rates were 91.7 ％ ( 55/60 ) and 71.7％ ( 43/60 ),respectively.The difference was significant (x2 =8.541,P ＜ 0.05).Conclusions The patients with heart failure and gefractory to conventional treatment will benefit from diuretic mixture treatment,with the advantages of safety and economy.
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The course, distribution of the intrathalamic vessels on 8 sides of newborn brains were studied by means of the continuous artery-vein infusion, Spalteholz's clearing and Nissl's staining. The brains were all cut into the coronal sections of 500 ?m, 100?m and 30?m thickness in alternate and successive order. The main arteries supplying thalamic nuclei were: 1. The thalamoperforating artery; 2. The geniculothalamic artery; 3. The medial posterior choroidal artery; 4. The medial inferior pulvinar artery; 5. The lateral ventricular choroidal artery. The thalamic veins opened respectively into the internal cerebral vein, the veins of the lateral ventricle, the veins of the interpeduncular fossa and the basal vein. There were three patterns of course relation between thalamic arteries and veins. They were solitariness, accompanying and one vein surrounded by several arteries.
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The brains from four newborns were used in this study. After continuous artery-vein injection with coloured materials, the brains were embedded in nitrocellulose. and coronal sections of 500?m, 100?m and 30?m in thickness were prepared in alternative and successive sequence. The 500?m sections were cleared in wintergreen oil and mounted, and the 100?m and 30?m sections were stained with thionin. The diameter and density of capillaries in thalamus and its adjacent structures were measured by means of Leitz MPV-Tasplus multifunction image analyser. All the data were dealt with variance and correlation analysis statistically. The capillary density of the thalamus and its adjacent structures varied obviously. The value in putamen, cellular layers of lateral geniculate body, anterior thalamic nucleus and subthalamic nucleus was the highest; while the value in dorsomedial nucleus, ventral lateral nucleus, pulvinar nucleus, ventral posterior lateral nucleus, lateral posterior nucleus, centromedian nucleus, medial geniculate body, ventral anterior nucleus and internal medullary lamina was the intermediate; however, the value in internal capsule and fibrous layers of lateral geniculate body was the lowest. The capillary diameter of ventral anterior nucleus and internal capsule was the widest; that of putamen and cellular layers of lateral geniculate body was the smallest; the rest was the intermediate. In the same measured structures, negtive correlation was shown between the capillary diameter and density.