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Objective:To investigate the effect of multiple-modality exercise on symptom clusters and nutritional status of nasopharyngeal carcinoma patients with radiotherapy.Methods:A total of 92 nasopharyngeal carcinoma patients who received radiotherapy in the Panzhihua Center hospital were randomly divided into research group and control group, each group contained 46 cases. The control group received routine nursing and the research group received 4-week multiple-modality exercise. The scores of M.D. Anderson symptom inventory-head & neck module (MDASI-H&N), patient-generated subjective global assessment (PG-SGA) and other biochemical nutrition index were compared before and after intervention between two groups.Results:After intervention, the scores of fatigue, poor appetite, dry mouth, mouth/throat mucus, dysgeusia were 3.77±1.30, 3.48±1.22, 3.81±1.48, 4.24±0.83, 4.94±1.63 in the research group and 4.36±1.09, 4.52±1.25, 4.39±1.24, 4.24±0.83, 6.03±2.00 in the control group, respectively. Those scores were significantly decreased in the research group compared to the control group ( t value was 1.996-3.993, P<0.05). After 4 weeks of intervention, the PG-SGA total socres, body mass index, prealbumin, hemoglobin were 2.78±0.60, (22.08±2.61) kg/m 2, (199.60±27.16) mg/L, (105.59±17.62) g/L, those indexes were 4.14±1.08, (20.63±2.63) kg/m 2, (193.42±25.57) mg/L, (102.77±18.57) g/L, the total scores of PG-SGA were significantly decreased in the research group compared to the control group ( t value was 7.356, P<0.01). Conclusions:Multiple-modality exercise can alleviate symptom burden and promote nutritional status of nasopharyngeal carcinoma patients with radiotherapy.
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Objective To analyze the correlation of primary hyperuricemia and apolipoprotein E gene polymorphism between Hui and Han nationalities in Ningxia , and provide data for disease control and prevention .Methods Blood sam-ples,obtained from 900 cases at some medical institutions for case-control study, were detected for gene polymorphism of apolipoprotein E by connecting the enzyme reaction .Results and Conclusion There was no statistically significant differ-ence in the blood uric acid level in different nationality groups between the case group and the control group .Creatinine, fasting blood glucose, total cholesterol, triglycerides, and body mass index were considered risk factors of hyperuricemia . There was no statistically significant difference in apolipoprotein E genotype and allele frequency between different nationali -ties and genders in case group and control group .There might be no correlation of primary hyperuricemia and apolipoprotein E gene polymorphism .