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Objective To observe the effect of herbal recipe Zhiganqing capsule(ZGQ capsule) in treating non-alcoholic fatty liver disease(NAFLD).Methods One hundred and twenty NAFLD patients were divided into two groups randomly.On the basis of diet control and increasing exercise,the treating group was treated with ZGQ capsule,and the control group was treated with Dongbao Gantai pill.The effect and side effects were observed after 4 months.Results The curing rate and total effective rate of treatment group and control group were 51.67%,93.33% and 13.34%,53.33% respectively,the difference between the two groups was significant(P
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Objective To observe the effect of Xiaogu Ruanjian pills on hepatic histopathology and epidermal growth factor (EGF) of liver cirrhosis rats. Methods The rats model of cirrhosis was made by complex factors,compared with Fufang Biejia Ruanganpian,the effect of Xiaogu Ruanjian Pills on hepatic pathology and EGF were observed. Results Compared with the normal group,extensive fibrous tissue hyperplasia can be seen in hepatic mesenchyme of the model group,the liver pseudolobule formed,and the contents of EGF in serum and liver were increased (P
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Objective To research the effect of Xiaoguruanjian pill on liver cirrhosis ascites patients and the regulation on blood NO and ET-1. Methods 133 liver cirrhosis ascites were divided into two groups randomly. 45 cases of the control group were treated with routine western medicine according to the patients state of illness, 88 cases of the treatment group were treated with Chinese herbal compounds Xiaoguruanjian Pill on the basis of routine western medicine. The total effective rate, liver function test, ultrasonogram of liver and spleen, the contents of blood NO and ET-1 of two groups were detected before and after the treatment, and the effect on blood NO and ET-1 of patients with SBP and renal dysfunction were observed too. Results There was a significant difference between the two groups in the total effective rate, improvement of the liver function test, ultrasonogram of portal vein diameter and spleen, and the regulation of blood NO and ET-1 level (P