Comparative analysis of essential oil and fatty acid constituents of Abrus cantoni-ensis and Abrus mollis / 药学实践杂志

Objective To utilize and evaluate the resources of Abrus cantoniensis Hance (AC) and Abrus mollis Hance (AM ) by analyzing and comparing their essential oils and fatty acids .Method The essential oils of AC and AM were extracted with the hydro distillation method .Fatty acids were obtained by petroleum ether extraction of the 95% ethanol concentrate . Fatty acid extract was further reacted with BSTFA for GC-MS analysis .Components were identified by searching NIST MS library .Result Forty-two and thirty-three chemical constituents were identified from the essential oil of AC and AM respec-tively ,which accounted for 56 .76% and 63 .45% of their volatile components .( ± )-α-terpinyl acetate are the common essential oils found in both AC and AM .Thirteen and fourteen chemical constituents were identified from the fatty acid extract of AC and AM respectively .AC and AM have different chemical components and compositions .Conclusion Our results provide a sci-entific basis for the bioactivities ,quality control and resource utilization of AC and AM .

Research on the pharmaceutical intellectual property protection and supervision of pharmacy administration

The patent system plays an important role in the pharmaceutical industry. In this paper, the authors analyze the pharmaceutical intellectual property protection and supervision of pharmacy administration. The intellectual property rights of drugs shall be granted to the inventor in accordance with the law, however, the pharmaceutical industry is concerned with the public health and social welfare. Therefore, we focus on the analysis of patent compulsory licensing system in the protection of intellectual property rights. Through case studies, we can see that although many countries do not implement compulsory licensing system, but this system still can become the chip for all countries to obtain authorization or reduce drug price

TLC Fingerprints of Chloroform Extract of Compound Herba Taraxaci Enemas:Comparison between Batches / 中国药房

OBJECTIVE: To compare TLC fingerprints between different batches of compound Herba taraxaci enemas (CHTE) ant to lay a foundation for establishing a more stable preparation technics and quality standards for CHTE. METHODS: The chloroform extract of 2 batches of CHTE were chromatographed by TLC and the samples were scanned by TLC scanner at a single wavelength of 280nm,the difference between different batches was compared. RESULTS: The TLC of chloroform extracts was well-separated,there were 6 common peaks and 2 non-common peaks in the TLC of 2 batches of samples, with some of the peaks identified in terms of the medicinal material categories, but there was a significant difference in contents among the common peaks. CONCLUSIONS: It was hard to guarantee the relative conformity in numbers of components and the contents between different batches of preparations,the preparation technics and quality standard of raw materials remain to be further optimized and the quality standard for Chinese herb medicinal preparations in hospital should be improved further.

Identification of proteins and polypeptides from Fructus Lycii by HPCE / 中国药学杂志

BJECTIVE　To identify the fruits of Lycium barbarum L.(LB) and Lycium chinense Mill.(LC).METHODS　The proteins and polypeptides from the fruits of LB and LC were analysed by high-performance capillary electrophoresis.RESULTS　LB could be distinguished from LC by their electrophorograms.CONCLUSION　HPCE could be used for the pharmacognostic identification of Fructus Lycii.