RESUMO
Objective:To explore the distribution of psychological aging in healthy population and its relationship with telomere length in peripheral blood leukocyte,and to provide reference for aging evaluation.Methods:Stratified random samples were obtained according to age and they were divided into 9 age groups.The age-related psychological information were collected from healthy people by using the self-made scale.Situation of psychological aging,correlation between age and telomere length and score of this scale were analyzed by statistical software.Results:A total of 2 100 questionnaires were distributed,and 2 060 of them were valid and has been recovered,with an efficiency of 98.10％.The ratio of male to female was 0.95:1;psychological aging score was in the range of 8.62-23.14;cognitive function score was in the range of 2.25-10.77;emotion score was in the range of 1.45-6.73;personality score was in the range of 0.96-4.22;motivation score was in the range of 1.50-7.18.The correlation coefficient of psychological aging scores with age was 0.721 (P＜0.001).The average relative telomere length was 1.06±0.26,and relative telomere length in different age groups were significantly different (F=35.803,P＜0.001).Telomere length was negatively correlated with age (r=-0.964,P＜0.00 1) and psychological agingscores (r=-0.915,P=0.004).Conclusion:The empirical study of physiological aging scale in healthy population shows that the scores of physical aging are increased with age and that the telomere length is negatively correlated with aging scores,suggesting that the scale can provide reference for the comprehensive evaluation of aging.
RESUMO
Objective To explore the application value of telepathological consultation in helping grassroots hospitals.Methods 578 cases of intraoperative telepathology consultation were reviewed,and the accuracy and the timely rate of diagnosis were calculated.The systematic distribution,benign and malignant distribution,and the distribution difference in different primary hospitals were analyzed,so as to evaluate the popularization value of the intraoperative telepathology consultation.Results The accuracy rate of 578 cases of intraoperative telepathology consultation was 99.83％.The timely rate of consultation in 30min was 96.02％,and most reports could be diagnosed in 2 to 5 mins.The source of tissues involved in consultation were thyroid,breast,ovary/fallopian tube and lung.In all cases,24.39％ of the malignant tumors were found.Among the diseases of different systems,the proportion of malignant tumors is the highest in breast diseases,followed by lung,thyroid and ovary.Among the four hospitals with most of the consultations,the rate of malignant tumor in Renmin Hospital of Jianli County was the highest,followed by Renmin Hospital of Yingshan County,Renmin Hospital of Xiaochang County,and Fifth Division Hospital of Xinjiang.Conclusion Intraoperative telepathology consultation can provide accurate and timely expert consultation for grassmots hospitals,avoid the "second operations" of the patients,improve the access of medical treatment for people living in relatively remote areas,solve the shortage of pathologists at the grassroots hospitals,and improve the level of doctors' diagnosis and treatment at the grassroots hospitals,which is worth popularizing and applying in Pathology Department of the grassroots hospitals.
RESUMO
To investigate the ageing status for male population aged or over 20 years old in urban communities, clarifying their distribution characteristics and rules, and to provide reference for aging research. Methods: A total of 1 120 men aged or over 20 years old in Nanchang were obtained by stratified sampling, and the aging scale was measured in 9 groups. The distribution characteristics of aging scores were analyzed by normality test, variance analysis, and linear correlation. Results: The total score of aging and the scores of physiological, psychological, and physiological dimensions were 54.01±9.24, 32.33±7.54, 14.66±1.64, and 7.02±1.16, respectively. The scores were positively correlated with age. The total score curve of aging was significantly increased in the 25-<30 and 30-<40, 65-<70 and 70-<75 years old groups. The physiological dimension curve was similar to the total score curve. The psychological dimension curve was more pronounced at 55-<60 and 60-<65 years old groups. The social dimension curve raised slowly and smoothly at all ages. Conclusion: The total score and the scores for all dimensions of male physiological-psycho-sociological increase with age; and changes near the age group of 55-<60 and 60-<65 are obvious, providing reference for the understanding of male aging.
Assuntos
Adulto , Idoso , Humanos , Masculino , Pessoa de Meia-Idade , Adulto Jovem , Distribuição por Idade , Envelhecimento , Fisiologia , PsicologiaRESUMO
To explore the relationship between telomere length changes and age, and to provide data and reference for further study of geriatric medical problems. Methods: The healthy people over 20 years old were chosen as subject from several hospitals by random sampling method, and their peripheral blood samples were collected. The relative length of telomere was detected by quantitative real-time PCR, and the relationship between age and telomere length was analyzed by statistical software. Results: A total of 1 022 samples were obtained. There were significant differences in the relative telomere length among different age groups (F=21.492, P<0.001). Telomere length and age showed negative correlation (r=-0.325, P<0.001), the regression equation was y=-0.008x+1.772 (x for age, y for the average telomere length, P<0.001). Conclusion: The telomere length for peripheral blood leukocytes in healthy people varies between different age groups, suggesting that telomere length gradually decreases with age.