Latest advancement in designing and evaluation of MDR inhibitors targeting P-glycoprotein / 国外医学(肿瘤学分册)

Over-expression of P-glycoprotein (Pgp) is associated with the development of multi-drug resistance ( MDR). Pgp has been focused on as the main target in designing chemotherapy strategy. In this article we review some of the latest advancement in designing and evaluation methods of P- glycoprotein inhibitors.