RESUMO
Clinical trials play an important role in guiding clinical practice .Over the past decade , Chinese investigators on lung cancer have not only participated and gradually taken a leadership in international multi -center clinical trials , but also established the first multi-center collaborative clinical trial group in China , which has promoted the development of new anti-cancer drugs , the for-mation of new treatment strategies and the innovation of clinical trial designs .Taking epidermal growth factor receptor-tyrosine kinase inhibitors, we focus on the clinical trials on lung cancer aimed at reshaping the clinical practice strategies in China or even worldwide with the participation or leadership of Chinese researchers as well as current challenges and future prospects in lung cancer studies .