A new coumarin from flowers of Edgeworthia gardneri / 中草药

Objective: To study the chemical constituents from the flowers of Edgeworthia gardneri. Methods: The chemical constituents were isolated and purified by column chromatography on silica gel, AB-8 macroporous resin, sephadex LH-20, pre-HPLC. Their structures were determined on the basis of physicochemical properties and spectral analysis. Results: Four compounds were isolated from the flowers of E. gardneri and elucidated as gardnerol C (1), daphnoretin-5-O-β-D-glucopyranosyl- (1→2)-β-D-glucopyranoside (2), (3S)-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid (3), and dihydrokaempferol (4). Conclusion: Compound 1 is a new coumarin named gardnerol C, and compound 4 is obtained from the genus for the first time.