RESUMO
This article summarized the chemical constituents and pharmacological activities of Lysimachia L., thus providing scientific and theoretical basis for development of this genus. Literatures of experimental studies on Lysimachia genus at home and abroad were consulted and summarized. The chemical research showed that the main compounds in Lysimachia genus were triterpenoids and their glycosides, flavonoids and their glycosides, organic acids, and sterols. Pharmacological investigation showed that the plants of this genus had anti-tumor, anti-inflammatory, antioxidant, and α-glucosidase inhibitory activities. Lysimachia genus should be further researched and utilized, which is abundant in our country.
RESUMO
Objective: To study the chemical constituents from the whole plant of Actinostemma lobatum. Methods: The compounds were isolated and purified by various column chromatographies. Their structures were elucidated by means of chemical evidences and spectral analyses (MS, 1H-NMR, and 13C-NMR). Results: Sixteen compounds were isolated and identified as actinostemmoside A (1), actinostemmoside C (2), actinostemmoside D (3), actinostemmoside E (4), cucurbitacin E (5), β-sitosterol (6), daucosterol (7), α-spinasterol (8), α-spinasterol-3-O-β-D-glucopyranoside (9), 22, 23-dehydroxy-α-chondrillasterone (10), quercetin (11), kaempferol (12), rutin (13), quercitrin (14), kaempferol-3-O-α-L-rhamnopyranosyl (1→6)-β-D-glucoypyranoside (15), and isoquercitrin (16). Conclusion: Compounds 5-10 are obtained from this genus for the first time.