Importance of Conservative Management in Borderline Malignancy of the Ovary / 대한부인종양콜포스코피학회잡지

OBJECTIVES: To clarify the clinicopathologic features of borderline malignancy of the ovary and analyze the treatment and survival characteristics through the study of our cases. Study METHODS: 102 patients with borderline tumors of the ovary, aged from 14 to 79 years, treated between 1982 and 1999 at Seoul National University Hospital, were analyzed retrospectively for clinicopathologic features. Most informations about stage, treatment modality and prognosis were obtained by hospital record or contacting patient with telephone. RESULTS: There were 77 patients (75.5%) with stage Ia, 5 stage Ib, 11 stage Ic, 4 with stage II and 5 with stage III by the classification of FIGO. 72 patients (70.6%) were mucinous type and 28 (27.5%) were serous type, 1 endometrioid type, 1 mixed. Total abdominal hysterectomy, bilateral adnexectomy, and omentectomy were performed in 43 (42.2%) patients and fertility saving surgery in 43 patients(cystectomy in 11 patients, USO in 32 patients). Twenty two patients (21.6%) were treated with postoperative adjuvant chemotherapy. The median duration of follow up was 54.0 months (1-204 months) and 6 patients developed recurrence after several years from the primary operation. The ten-year eumulative survival rate was 92.2% and the only independent prognostic factors evaluated by Cox analysis in regards to corrected survival were the FIGO stage (p=0.0197). There was no difference in the ten-year survival rate between surgery types - conservative surgery versus full surgical staging. And there was no difference in the 10-year survival rate between treatment groups - surgery only versus surgery followed by adjuvant chemotherapy. CONCLUSIONS: FIGO stage is the only independent prognostic factor in the borderline ovarian tumors. There was no difference in the 10-year survival rate of barderline ovarian tumors between surgery alone versus surgery followed by adjuvant chemothearpy. The slow clinical course, low recurrence rate and good prognosis in our patients explained again the reason for therapeutic approach relying on surgery alone.

Study on 10 Year Follow-up after Radical Gastrectomy for Stomach Cancer

A retrospective study was made from 468 cases of stomach cancer from January 1980 to December 1985 in Gospel Hospital, Kosin Medical College. The purpose of this report is to clarrify the 10 year survival rate and prognostic factors. The results were as follows: 1) There was a male preponderance with a male to female ratio of 1.7:1. The peak incidence of age was 6th decade. 2) In 468 radical gastrectomized patients, the most common primary site was lower one-third of stomach(61.2%). 3) About stage distributions, 8.8% of patients were in stage Ia, 19.7% in Ib, 26.5% in II, 24.1% in IIIa, 17.5% in IIIb and 3.4% in IV. 4) The 10 year survival rates according to T and N factors were 86.4% in T1, 54.4% in T2, 37.4% in T3, and 15.6% in T4 ; 64.5% in N0, 32.5% in N1, and 18.4% in N2(P=0.0001) 5) The 10 year survival rates according to methods of operation were 46.5% in subtotal gastrectomy and 15.3% in total gastrectomy. 6) The 10 year survival rates according to WHO pathologic classification were 20% in papillary, 47.2% in well differentiated tubular, 48.2% in moderately differentiated tubular, 32.4% in poorly differentiated, 32.1% in mucinous, and 25.0% in signet ring cell type. 7) The 10 year survival rates according to Lauren classification were 46.3% in intestinal, 28.9% in diffuse, and 38.7% in mixed type.