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Braz. J. Pharm. Sci. (Online) ; 58: e20556, 2022. tab, graf
Artigo em Inglês | LILACS | ID: biblio-1403704

RESUMO

Abstract Tetradenia riparia (Hochst.) Codd (Lamiaceae) is a species native to the African continent and used as an insect repellent. The objective of the study was to evaluate the larvicidal potential of essential oils (EOs) from the leaves, flower buds, and stem of T. riparia, collected in winter against Aedes aegypti larvae. The EOs were extracted by hydrodistillation (3 h) and identified by GC/MS. The EOs were tested against larvae of A. aegypti at concentrations ranging from 12500 to 1.5 µg/mL for 24 h. The insecticide activity was evaluated by probit analysis, and the anticholinesterase activity was determined by bioautographic method. The results of the class projection indicated sesquiterpenes as the majority class, corresponding to 60.66% (leaves), 64.70% (flower buds) and 83.99% (stem), and the bioassays on A. aegypti larvae indicated LC50 of 1590, 675 and 665 µg/mL, respectively. The anticholinesterase activity indicated that the EO of the leaves inhibited the enzyme at a concentration of 780 µg/mL, and those from the flower buds and stem inhibited up to 1560 µg/mL. The results indicated weak activity of essential oils against A. aegypti larvae.


Assuntos
Óleos Voláteis/efeitos adversos , Caules de Planta/efeitos adversos , Folhas de Planta/efeitos adversos , Lamiaceae/metabolismo , Aedes/classificação , Flores/efeitos adversos , Repelentes de Insetos/análise , Larva/crescimento & desenvolvimento , Inibidores da Colinesterase/administração & dosagem , Microscopia Eletrônica de Transmissão e Varredura/métodos
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